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BYU vs Colorado Prediction 9/27/2025 Today’s College Football Picks

Sep 20, 2025; Boulder, Colorado, USA; Colorado Buffaloes quarterback Kaidon Salter (3) reacts as he scores a rushing touchdown in the fourth quarter at against the Wyoming Cowboys Folsom Field. Mandatory Credit: Ron Chenoy-Imagn Images

Sep 20, 2025; Boulder, Colorado, USA; Colorado Buffaloes quarterback Kaidon Salter (3) reacts as he scores a rushing touchdown in the fourth quarter at against the Wyoming Cowboys Folsom Field. Mandatory Credit: Ron Chenoy-Imagn Images

MATCHUP Cougars BYU Buffaloes Colorado
Team Records 3-0 2-3
Where Folsom Field, Boulder, CO
When Saturday, September 27, 2025
Time 10:15 PM EDT
TV ESPN

The BYU Cougars and Colorado Buffaloes meet Saturday in college football action at Folsom Field. Here’s a BYU vs Colorado Prediction. This article will include a BYU vs Colorado Pick.

BYU Cougars Betting Preview

The BYU Cougars beat Stanford and East Carolina, and they play West Virginia next. BYU has won 5 straight games. Bear Bachmeier is completing 66.7 percent of his passes for 518 yards, 4 touchdowns, and 0 interceptions. Chase Roberts and Carsen Ryan have combined for 331 receiving yards and 3 touchdowns, while Parker Kingston has 9 receptions.

The BYU Cougars ground game is averaging 265.7 yards per contest, and LJ Martin leads the way with 342 yards and 1 touchdown. Defensively, BYU is allowing 5.3 points and 205.3 yards per game. Logan Lutui leads the BYU Cougars with 15 tackles, Jack Kelly has 3 sacks and Evan Johnson has 2 interceptions.

Colorado Buffaloes Betting Preview

The Colorado Buffaloes lost to Houston, beat Wyoming, and they play TCU next. Colorado has won 10 of its last 15 games. Kaidon Salter is completing 66.7 percent of his passes for 565 yards, 4 touchdowns, and 0 interceptions. Sincere Brown and Omarion Miller have combined for 384 receiving yards and 3 touchdowns, while Joseph Williams has 9 receptions.

The Colorado Buffaloes ground game is averaging 141.3 yards per contest, and Kaidon Salter leads the way with 153 yards and 3 touchdowns. Defensively, Colorado is allowing 22.5 points and 409.3 yards per game. Tawfiq Byard leads the Colorado Buffaloes with 27 tackles, Arden Walker has 1.5 sacks and RJ Johnson has 1 interception.

BYU Cougars @ Colorado Buffaloes Betting Trends: Week 5

Why the Colorado Buffaloes will win

Why the BYU Cougars will win

Total Points Facts

Colorado Buffaloes Player Prop Facts

BYU Cougars Player Prop Facts

Matchup/League Facts

BYU vs Colorado Prediction

BYU hasn’t had the toughest schedule up to this point, but it’s proven to e one of the more balanced teams in the country. BYU is top-20 in scoring offense and second in both total defense and scoring defense. Meanwhile, Colorado still has questions at quarterback and struggles to finish drives, while the defense can’t stop the run and is 112th in total defense. BYU crushed Colorado back in December by 22 points, and you can argue the Buffaloes were far more talented than they are this season. The crowd will be out and Colorado has moments where it can hang around, but BYU is too consistent on both sides of the ball. I’ll lay the points.

Randy Chambers's Pick: BYU -6.5

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