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Pittsburgh vs West Virginia Prediction 9/13/2025 Today’s College Football Picks

Sep 6, 2025; Athens, Ohio, USA; West Virginia Mountaineers running back Jahiem White (1) runs the ball and is tackled by Ohio Bobcats safety Adonis Williams Jr. (5) during the first quarter at Peden Stadium. Mandatory Credit: Ben Queen-Imagn Images

Sep 6, 2025; Athens, Ohio, USA; West Virginia Mountaineers running back Jahiem White (1) runs the ball and is tackled by Ohio Bobcats safety Adonis Williams Jr. (5) during the first quarter at Peden Stadium. Mandatory Credit: Ben Queen-Imagn Images

MATCHUP Panthers Pittsburgh Mountaineers West Virginia
Team Records 2-1 2-1
Where Milan Puskar Stadium, Morgantown, WV
When Saturday, September 13, 2025
Time 03:30 PM EDT

The Pittsburgh Panthers and West Virginia Mountaineers meet Saturday in college football action at Milan Puskar Stadium. Here’s a Pittsburgh vs West Virginia Prediction. This article will include a Pittsburgh vs West Virginia Pick.

Pittsburgh Panthers Betting Preview

The Pittsburgh Panthers beat Duquesne and Central Michigan, and they play Louisville next. Pittsburgh has split its last 12 games. Eli Holstein is completing 70.6 percent of his passes for 519 yards, 8 touchdowns, and 2 interceptions. Raphael Williams Jr. and Cataurus Hicks have combined for 240 receiving yards and 4 touchdowns, while Desmond Reid has 6 receptions.

The Pittsburgh Panthers ground game is averaging 141 yards per contest, and Desmond Reid leads the way with 112 yards and 1 touchdown. Defensively, Pittsburgh is allowing 13 points and 212.5 yards per game. Rasheem Biles leads the Pittsburgh Panthers with 15 tackles, Kyle Louis has 2 sacks and Rashad Battle has 1 pass deflection.

West Virginia Mountaineers Betting Preview

The West Virginia Mountaineers beat Robert Morris, lost to Ohio, and they play Kansas next. West Virginia has split its last 12 games. Nicco Marchiol is completing 69.6 percent of his passes for 402 yards, 1 touchdown, and 1 interception. Cam Vaughn and Jaden Bray have combined for 265 receiving yards and 1 touchdown, while Grayson Barnes has 4 receptions.

The West Virginia Mountaineers ground game is averaging 232.5 yards per contest, and Jahiem White leads the way with 133 yards and 3 touchdowns. Defensively, West Virginia is allowing 10 points and 276 yards per game. Fred Perry leads the West Virginia Mountaineers with 15 tackles, Chase Wilson has 3 sacks and Darrian Lewis has 1 interception.

Pittsburgh Panthers @ West Virginia Mountaineers Betting Trends: Week 3

Why the West Virginia Mountaineers will win

Why the Pittsburgh Panthers will win

Total Points Facts

West Virginia Mountaineers Player Prop Facts

Pittsburgh Panthers Player Prop Facts

Matchup/League Facts

Pittsburgh vs West Virginia Prediction

Pittsburgh is the better team obviously as West Virginia has taken a step back these last couple of years and is coming off a bad loss to Ohio. However, we’re getting a home team and a free touchdown in a rivalry game. The underdog is 5-2-1 ATS in the last 8 games between Pittsburgh and West Virginia. Pittsburgh is 6-0 ATS as a road favorite of 5 or more points, but there’s value with points in a rivalry where teams are familiar with each other and don’t particularly like one another. I’ll grab the free touchdown with the Mountaineers.

Randy Chambers's Pick: West Virginia +7.5

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