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San Diego State vs Northern Illinois Prediction 9/27/2025 Today’s College Football Picks

Sep 5, 2025; College Park, Maryland, USA;  Northern Illinois Huskies quarterback Josh Holst (15) in action against the Maryland Terrapins at SECU Stadium. Mandatory Credit: Jamie Sabau-Imagn Images

Sep 5, 2025; College Park, Maryland, USA; Northern Illinois Huskies quarterback Josh Holst (15) in action against the Maryland Terrapins at SECU Stadium. Mandatory Credit: Jamie Sabau-Imagn Images

MATCHUP Aztecs San Diego State Huskies Northern Illinois
Team Records 3-1 1-3
Where Huskie Stadium, Dekalb, IL
Time Sep 27th, 7:30 PM Z
TV ESPN+

The San Diego State Aztecs and the Northern Illinois Huskies meet in week 5 college football action from Huskie Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego State Aztecs vs. Northern Illinois Huskies prediction.

San Diego State Aztecs Recap

The San Diego State Aztecs come into this game looking to add on to their 34-0 win over Cal last time out to sit at 2-1 this season. After this game, San Diego State will head home for a game against Colorado State.

Aztecs Coming Off Of Huge Shutout Of Golden Bears

Jayden Denegal has thrown for 529 yards and 3 touchdowns on 58.9% passing while Lucky Sutton leads the Aztecs on the ground with 249 rushing yards and 3 touchdowns so far this season. Jordan Napier leads San Diego State in receiving with 19 grabs for 241 yards and a touchdown while Jacob Bostick also has 126 receiving yards on 10 catches with 2 touchdowns. On defense, Owen Chambliss has a team-high 23 total tackles including 16 solo tackles while August Salvati has a team-high 3.5 sacks so far this season.

Northern Illinois Huskies Recap

The Northern Illinois Huskies come into this one looking to rebound from their 38-10 loss at the hands of the Mississippi State Bulldogs last time out to sit at 1-2 this season. After this game, Northern Illinois will head home for a game against Miami-Ohio.

Huskies Drop Back-To-Back Outings

Josh Holst has thrown for 327 yards a touchdown and 2 interceptions on 63.5% passing while Chavon Wright leads the Huskies in rushing with 214 yards and a touchdown and Telly Johnson Jr. has 199 rushing yards with a touchdown as well this season. DeAree Rogers has a team-high 16 catches for 173 yards as well this season. On defense, Quinn Urwiler has a team-high 34 total tackles including 17 solo tackles while NIU’s defense as a whole has combined for 4 sacks and an interception so far this season.

San Diego State Aztecs @ Northern Illinois Huskies Betting Trends: Week 5

Why the Northern Illinois Huskies will win

Why the San Diego State Aztecs will win

Total Points Facts

Northern Illinois Huskies Player Prop Facts

San Diego State Aztecs Player Prop Facts

Matchup/League Facts

San Diego State Aztecs vs. Northern Illinois Huskies Prediction

I’m on San Diego State here. I just don’t trust Northern Illinois offensively. Granted, boith of these teams have struggled mostly in their step up spots this season, but it’s also worth remembering that this is a Northern Illinois team that almost lost outright to Holy Cross to start the year. San Diego State has to really show something on the road, but I’ve been a lot more impressed with what I’ve seen from the Aztecs to this point and I think San Diego State gets the win and cover on the road here. Give me San Diego State.

Chris Ruffolo's Pick: San Diego State -2.5

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