Nov 7, 2025; Orlando, Florida, USA; Houston Cougars running back Dean Connors (44) catches a pass in front of UCF Knights defensive back Antione Jackson (7) during the second half at Acrisure Bounce House. Mandatory Credit: Mike Watters-Imagn Images
Mike Watters-Imagn Images

TCU vs Houston Prediction 11/22/2025 Today’s College Football Picks

Pick details

MATCHUP TCU Horned Frogs Houston Cougars
Team Records 6-4 8-2
Spread +1.5 -118 -1.5 -102
Moneyline -105 -115
Total Over 54.5 (-118) Under 54.5 (-102)
Where TDECU Stadium, Houston, TX
When Saturday, November 22, 2025
Time 04:00 PM EST
TV FOX

In this article, we will formulate a TCU vs Houston Prediction for this College Football Week 13 game on Saturday, November 22nd. Let’s take a look at the prediction for this College Football matchup.

Houston Cougars Preview


Houston has an 8-2 record this season and is sitting 4th in the Big 12. They are 7-3 ATS, 7-3 in Over/Under and have a 3-2 home record and a 5-0 away record. Houston is coming off a 30-27 road win against UCF and will face Baylor next.

Offensively, Houston averages 29.5 points per game, ranking 60th in the nation, while defensively, they allow 22.1 points per game, which is 47th. Houston averages 388.3 total yards per game (222.1 passing and 166.2 rushing), while allowing 333.1 total yards per game (135.5 rushing and 197.6 passing).

Conner Weigman leads Houston with 2,113 passing yards with 64.9% completed passes and 18 touchdowns. Dean Connors leads the team in rushing yards with 725, while Tanner Koziol has a team-high 56 receptions for 570 receiving yards. Defensively, Carlos Allen has a team-high 67 total tackles (28 of them solo), while Eddie Walls III leads the team in sacks, with 5.5, and Latreveon McCutchin has a team-high 2 interceptions.

TCU Horned Frogs Preview


TCU has a 6-4 record this season and is sitting 10th in the Big 12. They are 4-6 ATS, 5-5 in Over/Under and have a 4-1 home record and a 2-3 away record. TCU is coming off a 44-13 road loss against BYU and will face Cincinnati next.

Offensively, TCU averages 30.7 points per game, ranking 48th in the nation, while defensively, they allow 26.5 points per game, which is 84th. TCU averages 413.4 total yards per game (291.4 passing and 122 rushing), while allowing 373.7 total yards per game (126.7 rushing and 247.0 passing).

Josh Hoover leads TCU with 2,873 passing yards with 64.0% completed passes and 23 touchdowns. Kevorian Barnes leads the team in rushing yards with 443, while Eric McAlister has a team-high 52 receptions for 941 receiving yards. Defensively, Kaleb Elarms-Orr has a team-high 99 total tackles (46 of them solo), while Kaleb Elarms-Orr leads the team in sacks, with 4, and Jamel Johnson, Bud Clark have a team-high 4 interceptions each.

TCU Horned Frogs @ Houston Cougars Betting Trends: Week 13


Why the Houston Cougars will win

  • Houston has won seven of its last eight games against non-AP-ranked teams.
  • TCU has lost each of its last four games against AP-ranked teams.
  • TCU has failed to cover the spread in seven of its last eight November games as a road underdog.
  • Houston has covered the spread in each of its last four games as a favorite against teams from Texas.

Why the TCU Horned Frogs will win

  • The underdog has won each of Houston’s last four games.
  • Houston has lost each of its last three November games as a favorite.
  • Houston has failed to cover the spread in each of its last five November games as a favorite.
  • The underdog has covered the spread in each of Houston’s last four games.
  • TCU has won the first half in six of its last eight road games against conference opponents.

Total Points Facts

  • Each of Houston’s last seven games against non-AP-ranked teams have gone OVER the total points line.
  • Each of TCU’s last four November games as a road underdog have gone OVER the total points line.

Houston Cougars Player Prop Facts

  • Heading into Week 13, Ethan Sanchez ranks T7th amongst FBS players for made field goals (19) this season.

TCU Horned Frogs Player Prop Facts

  • Heading into Week 13, Eric McAlister is one of only five players in the FBS to record 100+ receiving yards in three or more consecutive games this season.

Matchup/League Facts

  • Houston ranks 4th among FBS teams for Q3 opponent points per game this season (1.9).
  • Houston ranks 8th among FBS teams for red zone percentage this season (94.1).
  • TCU ranks 132nd among FBS teams for Q4 opponent points per game this season (10.2).
  • TCU ranks 126th among FBS teams for H2 opponent points per game this season (15.6).

TCU vs Houston Prediction


In this TCU vs Houston Prediction, Houston is coming as -1-point home favorites, with the total set at 55 points. Houston has more wins than TCU this season and is coming into this matchup in better form, having a 4-1 record in its last 5 games, while TCU has back-to-back losses. Houston is also 7-3 against the spread this season and are superior defensively, allowing 4.4 points fewer than TCU. Take Houston on the moneyline in this one.

Nikos Lagouretos's Pick: Houston ML

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