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TCU vs Houston Prediction 11/22/2025 Today’s College Football Picks

Nov 7, 2025; Orlando, Florida, USA; Houston Cougars running back Dean Connors (44) catches a pass in front of UCF Knights defensive back Antione Jackson (7) during the second half at Acrisure Bounce House. Mandatory Credit: Mike Watters-Imagn Images

Nov 7, 2025; Orlando, Florida, USA; Houston Cougars running back Dean Connors (44) catches a pass in front of UCF Knights defensive back Antione Jackson (7) during the second half at Acrisure Bounce House. Mandatory Credit: Mike Watters-Imagn Images

MATCHUP TCU Horned Frogs Houston Cougars
Team Records 6-4 8-2
Spread +1.5 -118 -1.5 -102
Moneyline -105 -115
Total Over 54.5 (-118) Under 54.5 (-102)
Where TDECU Stadium, Houston, TX
When Saturday, November 22, 2025
Time 04:00 PM EST
TV FOX
In this article, we will formulate a TCU vs Houston Prediction for this College Football Week 13 game on Saturday, November 22nd. Let’s take a look at the prediction for this College Football matchup.

Houston Cougars Preview


Houston has an 8-2 record this season and is sitting 4th in the Big 12. They are 7-3 ATS, 7-3 in Over/Under and have a 3-2 home record and a 5-0 away record. Houston is coming off a 30-27 road win against UCF and will face Baylor next.

Offensively, Houston averages 29.5 points per game, ranking 60th in the nation, while defensively, they allow 22.1 points per game, which is 47th. Houston averages 388.3 total yards per game (222.1 passing and 166.2 rushing), while allowing 333.1 total yards per game (135.5 rushing and 197.6 passing).

Conner Weigman leads Houston with 2,113 passing yards with 64.9% completed passes and 18 touchdowns. Dean Connors leads the team in rushing yards with 725, while Tanner Koziol has a team-high 56 receptions for 570 receiving yards. Defensively, Carlos Allen has a team-high 67 total tackles (28 of them solo), while Eddie Walls III leads the team in sacks, with 5.5, and Latreveon McCutchin has a team-high 2 interceptions.

TCU Horned Frogs Preview


TCU has a 6-4 record this season and is sitting 10th in the Big 12. They are 4-6 ATS, 5-5 in Over/Under and have a 4-1 home record and a 2-3 away record. TCU is coming off a 44-13 road loss against BYU and will face Cincinnati next.

Offensively, TCU averages 30.7 points per game, ranking 48th in the nation, while defensively, they allow 26.5 points per game, which is 84th. TCU averages 413.4 total yards per game (291.4 passing and 122 rushing), while allowing 373.7 total yards per game (126.7 rushing and 247.0 passing).

Josh Hoover leads TCU with 2,873 passing yards with 64.0% completed passes and 23 touchdowns. Kevorian Barnes leads the team in rushing yards with 443, while Eric McAlister has a team-high 52 receptions for 941 receiving yards. Defensively, Kaleb Elarms-Orr has a team-high 99 total tackles (46 of them solo), while Kaleb Elarms-Orr leads the team in sacks, with 4, and Jamel Johnson, Bud Clark have a team-high 4 interceptions each.

TCU Horned Frogs @ Houston Cougars Betting Trends: Week 13


Why the Houston Cougars will win

Why the TCU Horned Frogs will win

Total Points Facts

Houston Cougars Player Prop Facts

TCU Horned Frogs Player Prop Facts

Matchup/League Facts

TCU vs Houston Prediction


In this TCU vs Houston Prediction, Houston is coming as -1-point home favorites, with the total set at 55 points. Houston has more wins than TCU this season and is coming into this matchup in better form, having a 4-1 record in its last 5 games, while TCU has back-to-back losses. Houston is also 7-3 against the spread this season and are superior defensively, allowing 4.4 points fewer than TCU. Take Houston on the moneyline in this one.

Nikos Lagouretos's Pick: Houston ML

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