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UCLA vs Northwestern Prediction 9/27/2025 Today’s College Football Picks

Cincinnati Bearcats wide receiver Caleb Goodie (10) completes a pass in the first quarter of a NCAA men’s college football game between the Cincinnati Bearcats and Northwestern State Demons, Saturday, Sept. 13, 2025, at Nippert Stadium in Cincinnati.

Cincinnati Bearcats wide receiver Caleb Goodie (10) completes a pass in the first quarter of a NCAA men’s college football game between the Cincinnati Bearcats and Northwestern State Demons, Saturday, Sept. 13, 2025, at Nippert Stadium in Cincinnati.

MATCHUP Bruins UCLA Wildcats Northwestern
Team Records 0-4 2-2
Where Martin Stadium, Evanston, IL
When Saturday, September 27, 2025
Time 03:30 PM EDT
TV BTN

In this article, we will formulate a UCLA vs Northwestern Prediction for this College Football Week 5 game on Saturday, September 27th at the Northwestern Medicine Field at Martin Stadium. Let’s take a look at the prediction for this College Football matchup.

Northwestern Preview

Northwestern has a 1-2 record this season and are sitting on the 18th place of the Big Ten Conference. They are 2-1 ATS, 0-3 in Over/Under and have a 1-1 home record and 0-1 away record. The Wildcats are coming off a 14-34 home loss to Oregon and are playing Louisiana-Monroe and Penn State next.

Offensively, the Wildcats average 19.7 points per game, which ranks 115th in the nation. Defensively, they allow 21.3 points per game, which is 62nd. Northwestern averages 358.7 total yards per game, with 178.3 rushing yards and 180.3 passing yards per game. They allow 324.7 total yards per game, with 171.7 rushing and 153.0 passing yards per game.

Preston Stone leads the Wildcats with 541 passing yards and 59.3% completed passes. Caleb Komolafe leads the team in rushing yards, with 150, while Griffin Wilde has a team-high 15 caught passes for 213 receiving yards, and has zero touchdowns. Defensively, Robert Fitzgerald has a team-high 27 total tackles, 15 of them solo. Carmine Bastone leads the Wildcats in sacks, with 1.5, while Mac Uihlein has two interceptions.

UCLA Preview

UCLA has a 0-3 record this season and are sitting on the 11th place of the Big Ten Conference. They are 0-3 ATS, 1-2 in Over/Under and have a 0-2 home record and 0-1 away record. The Bruins are coming off a 10-35 home loss to New Mexico and are playing Northwestern, Penn State and Michigan State next.

Offensively, the Bruins average 14.3 points per game, which ranks 133rd in the nation. Defensively, they allow 36.0 points per game, which is 127th. UCLA averages 324.7 total yards per game, with 122.0 rushing yards and 202.7 passing yards per game. They allow 431.0 total yards per game, with 244.0 rushing and 187.0 passing yards per game.

Nico Iamaleava leads the Bruins with 608 passing yards and 63.9% completed passes. Anthony Woods leads the team in rushing yards, with 117, while Kwazi Gilmer has a team-high 16 caught passes for 174 receiving yards, and has zero touchdowns. Defensively, Isaiah Chisom has a team-high 37 total tackles, 17 of them solo. Kechaun Bennett leads the Bruins in sacks, with one.

UCLA Bruins @ Northwestern Wildcats Betting Trends: Week 5

Why the Northwestern Wildcats will win

Why the UCLA Bruins will win

Total Points Facts

Northwestern Wildcats Player Prop Facts

UCLA Bruins Player Prop Facts

Matchup/League Facts

UCLA vs Northwestern Prediction

In this UCLA vs Northwestern Prediction, Northwestern is coming as -6.5-point home favorites, with the total set at 45 points. UCLA has been terrible this season, having lost and failed to cover all of their three games played. They have a bottom-10 defense, and are losing by an average of 31.7 points per game. On the flip side, Northwestern has covered the spread in their last two games, and they are far better both offensively and defensively, so I expect them to get the job done today. Take Northwestern and lay the -6.5 points at home.

Nikos Lagouretos's Pick: Northwestern -6

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