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UNLV vs Wyoming Prediction 10/4/2025 Today’s College Football Picks
Pick details
UNLV (4-0) vs Wyoming (2-2)
October 4, 2025 at 07:00 PM EDT
The Line: Betting Odds: Wyoming +4.5 — Over/Under: +53.5
The UNLV Rebels and the Wyoming Cowboys meet Saturday in college football action from War Memorial Stadium. Here’s a UNLV vs Wyoming prediction. We will look at this from a betting perspective and determine the best UNLV vs Wyoming pick. We will examine:
The UNLV Rebels recent form and player performance
The Wyoming Cowboys recent form and player performance
Recent betting trends and streaks involving the UNLV Rebels
Recent betting trends and streaks involving the Wyoming Cowboys
Recent betting trends in games played between UNLV and Wyoming
A summary that ties it all together and produces a favorable betting outcome for the UNLV vs Wyoming game
The Rebels are cruising along quite well so far this year, sporting a 4-0 record. There hav e been a couple of very close calls along the way however, including the 38-31 opener win over Idaho State on August 23. UNLV had a bit more breathing room in their 38-21 victory over Sam Houston, but again had a one-score outcome in a 30-23 win over UCLA on September 6. In that one the Rebels committed 13 penalties for 130 yards in a sloppy overall game (the Bruins added 14 penalties for 129 yards). The defense also gave up 428 yards (255 passing) but held strong on third downs.
In their latest outing versus Miami-OH, the Rebels had another close outcome. UNLV overcame a 24-10 fourth-quarter deficit, rattling off 31 points for a wild comeback win 41-38. QB Anthony Colandrea finished 29-of-44 for 293 yards, two scores and two picks. Tops in rushing was Jai’Den Thomas with 118 yards and a touchdown on 14 carries, and Jaden Bradley had seven catches for 93 yards and a touchdown to lead the receivers in the wild victory.
Over on the Cowboys’ side, they’ve got four games in the books as well but have only been able to carve out a .500 record in that time. Wyoming got past Akron 10-0 in the opener and then took out Northern Iowa 31-7 in game two. The Utah matchup was the Cowboys’ first loss of the year however, as they faltered 31-6 in the end. Wyoming’s defense got pummeled pretty badly in that one, giving up 541 yards (311 rushing), 6.3 yards per play and 31 first downs. The Cowboys offense had a couple of turnovers and could only generate 229 yards themselves.
On September 20 in their latest appearance, the Cowboys gave up 21 points in the second quarter alone during a 37-20 defeat versus Colorado. QB Kaden Anderson finished just 11-of-25 for 176 yards and a couple of scores, while Samuel Harris carried 19 times for 126 yards rushing. Leading receiver Chris Durr posted five catches for 50 yards and a touchdown in the losing effort.
Heading into Week 6, Desman Hearns leads the Mountain West Conference for forced fumbles (1) this season.
Heading into Week 6, Troy Omeire ranks T1st amongst qualified players for catch rate (100.0%) this season.
Wyoming ranks T129th among FBS teams for Q1 points per game this season (1.8).
Wyoming ranks T127th among FBS teams for H1 points per game this season (5.8).
UNLV is one of 11 FBS teams to score 30+ points in every game this season.
UNLV ranks 124th among FBS teams for passing yards allowed per game this season (275.5).
I’ll take a stab on Wyoming, but you could call this one either way. The Cowboys could use a shot in the arm on both sides of the ball after their loss to Colorado, however. In that defeat Wyoming generated 347 yards with 20 first downs and 5-of-13 on third downs from their offense. The D gave up 497 yards (304 passing) and 8.4 yards per play on the other side. That makes two games with 10 or fewer points scored for the Cowboys, so it’d be nice to see the offensive unit get going here.
As for UNLV, they posted a furious comeback in the fourth quarter versus Miami-OH, eventually putting up 513 yards (220 rushing), 31 first downs and a very nice 12-of-17 success rate on third-down tries. That said, three of UNLV’s four wins have been decided by seven points or fewer. It seems the Rebels have been playing down to their opponents, which will benefit the Cowboys here.
The UNLV Rebels recent form and player performance
The Wyoming Cowboys recent form and player performance
Recent betting trends and streaks involving the UNLV Rebels
Recent betting trends and streaks involving the Wyoming Cowboys
Recent betting trends in games played between UNLV and Wyoming
A summary that ties it all together and produces a favorable betting outcome for the UNLV vs Wyoming game
UNLV Rebels Betting Preview
The Rebels are cruising along quite well so far this year, sporting a 4-0 record. There hav e been a couple of very close calls along the way however, including the 38-31 opener win over Idaho State on August 23. UNLV had a bit more breathing room in their 38-21 victory over Sam Houston, but again had a one-score outcome in a 30-23 win over UCLA on September 6. In that one the Rebels committed 13 penalties for 130 yards in a sloppy overall game (the Bruins added 14 penalties for 129 yards). The defense also gave up 428 yards (255 passing) but held strong on third downs.
In their latest outing versus Miami-OH, the Rebels had another close outcome. UNLV overcame a 24-10 fourth-quarter deficit, rattling off 31 points for a wild comeback win 41-38. QB Anthony Colandrea finished 29-of-44 for 293 yards, two scores and two picks. Tops in rushing was Jai’Den Thomas with 118 yards and a touchdown on 14 carries, and Jaden Bradley had seven catches for 93 yards and a touchdown to lead the receivers in the wild victory.
Wyoming Cowboys Betting Preview
Over on the Cowboys’ side, they’ve got four games in the books as well but have only been able to carve out a .500 record in that time. Wyoming got past Akron 10-0 in the opener and then took out Northern Iowa 31-7 in game two. The Utah matchup was the Cowboys’ first loss of the year however, as they faltered 31-6 in the end. Wyoming’s defense got pummeled pretty badly in that one, giving up 541 yards (311 rushing), 6.3 yards per play and 31 first downs. The Cowboys offense had a couple of turnovers and could only generate 229 yards themselves.
On September 20 in their latest appearance, the Cowboys gave up 21 points in the second quarter alone during a 37-20 defeat versus Colorado. QB Kaden Anderson finished just 11-of-25 for 176 yards and a couple of scores, while Samuel Harris carried 19 times for 126 yards rushing. Leading receiver Chris Durr posted five catches for 50 yards and a touchdown in the losing effort.
UNLV Rebels @ Wyoming Cowboys Betting Trends: Week 6
Wyoming Cowboys Player Prop Facts
Heading into Week 6, Desman Hearns leads the Mountain West Conference for forced fumbles (1) this season.
UNLV Rebels Player Prop Facts
Heading into Week 6, Troy Omeire ranks T1st amongst qualified players for catch rate (100.0%) this season.
Matchup/League Facts
Wyoming ranks T129th among FBS teams for Q1 points per game this season (1.8).
Wyoming ranks T127th among FBS teams for H1 points per game this season (5.8).
UNLV is one of 11 FBS teams to score 30+ points in every game this season.
UNLV ranks 124th among FBS teams for passing yards allowed per game this season (275.5).
UNLV vs Wyoming Prediction
I’ll take a stab on Wyoming, but you could call this one either way. The Cowboys could use a shot in the arm on both sides of the ball after their loss to Colorado, however. In that defeat Wyoming generated 347 yards with 20 first downs and 5-of-13 on third downs from their offense. The D gave up 497 yards (304 passing) and 8.4 yards per play on the other side. That makes two games with 10 or fewer points scored for the Cowboys, so it’d be nice to see the offensive unit get going here.
As for UNLV, they posted a furious comeback in the fourth quarter versus Miami-OH, eventually putting up 513 yards (220 rushing), 31 first downs and a very nice 12-of-17 success rate on third-down tries. That said, three of UNLV’s four wins have been decided by seven points or fewer. It seems the Rebels have been playing down to their opponents, which will benefit the Cowboys here.
