Oklahoma Sooners running back Taylor Tatum (8) runs past South Carolina Gamecocks defensive tackle Nick Barrett (93) during a college football game between the University of Oklahoma Sooners (OU) and the South Carolina Gamecocks at Gaylord Family - Oklahoma Memorial Stadium in Norman, Okla., Saturday, Oct. 19, 2024.

Virginia Tech vs South Carolina Prediction 8/31/2025 Today’s College Football Picks

Pick details

Virginia Tech (0-0) vs South Carolina (0-0)

August 31, 2025 at 03:00 PM EDT

The Line: Betting Odds: South Carolina -7.5 — Over/Under: +52.5

(Get latest betting odds)

In this article, we will formulate a Virginia Tech vs South Carolina Prediction for this College Football Week 1 game on Sunday, August 31st at the Mercedes-Benz Stadium. Let’s take a look at the prediction for this College Football matchup.

South Carolina Preview

South Carolina finished last season with a 9-4 overall record and had a 5-3 conference record in the SEC. Offensively last season, the Gamecocks scored 30.5 points per game, while allowing 18.1 points per game defensively. South Carolina averaged 184.4 rushing yards and 223.4 passing yards per game. They allowed 112.2 rushing yards per game and 204.4 passing yards per game.

LaNorris Sellers led the Gamecocks last season with 196/299 completed passes and 2,534 total passing yards. He also had 18 touchdowns and 7 interceptions. Robby Ashford had 23/32 passes for 324 passing yards and 2 touchdowns, while Davis Beville added 5/7 passes for 46 passing yards and 1 touchdown. Raheim Sanders led the team in rushing yards, with 881 and 11 touchdowns, while Joshua Simon had a team-high 40 caught passes for 519 receiving yards, and had 7 touchdowns. Nyck Harbor caught 26 passes for 376 yards, and 3 touchdowns.

Defensively, Nick Emmanwori had a team-high 88 total tackles, 57 of them solo, while Kyle Kennard had a team-high 11.5 total sacks, and Jalon Kilgore had a team-high 5 interceptions.

Virginia Tech Preview

Virginia Tech finished last season with a 6-7 overall record and had a 4-4 conference record in the ACC. Offensively last season, the Hokies scored 28.2 points per game, while allowing 22.8 points per game defensively. Virginia Tech averaged 178.4 rushing yards and 189.4 passing yards per game. They allowed 147.1 rushing yards per game and 215.9 passing yards per game.

Kyron Drones led the Hokies last season with 136/224 completed passes and 1,562 total passing yards. He also had 10 touchdowns and 6 interceptions. William Watson III had 34/58 passes for 481 passing yards and 1 touchdown, while Collin Schlee added 28/55 passes for 414 passing yards and 3 touchdowns. Bhayshul Tuten led the team in rushing yards, with 1,159 and 15 touchdowns, while Jaylin Lane had a team-high 38 caught passes for 466 receiving yards, and had 2 touchdowns. Da’Quan Felton caught 32 passes for 360 yards, and 2 touchdowns.

Defensively, Jaden Keller had a team-high 83 total tackles, 35 of them solo, while Antwaun Powell had a team-high 16 total sacks, and Mansoor Delane had a team-high 4 interceptions.

Virginia Tech vs South Carolina Prediction

In this Virginia Tech vs South Carolina Prediction, South Carolina is coming in as -7.5-point home favorites, with the total set at 52.0. South Carolina is coming off a nine-win season under Shane Beamer and has one of the top quarterbacks in the SEC and a roster that looks ready to push for CFP contention. On the flip side, Virginia Tech Virginia Tech is still working through some struggles under Brent Pry, especially against non-conference Power Four teams. The Gamecocks have the clear edge in this one, especially at a season opener at home. Take South Carolina to win and cover the spread. Take South Carolina by -7.5 points in this one.

Nikos Lagouretos's Pick: South Carolina -7.5

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