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Vanderbilt vs St. Mary’s Prediction 3/21/25 College Basketball Picks

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St. Mary's (28-5) vs Vanderbilt (20-12)

Game Info: Friday, March 21, 2025 at 3:15 pm (Rocket Arena)

The Line: Betting Odds: St. Mary's -4.5 — Over/Under: 135.5

(Get latest betting odds)

The Vanderbilt Commodores are facing the Saint Mary’s Gaels on Friday, March 21st at the Rocket Arena, in this NCAA Tournament Round of 64 matchup. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Vanderbilt Commodores vs Saint Mary’s Gaels Prediction. We will examine:

The Saint Mary’s Gaels recent form and player performance

The Vanderbilt Commodores recent form and player performance

Recent betting trends and streaks involving the Saint Mary’s Gaels

Recent betting trends and streaks involving the Vanderbilt Commodores

Recent betting trends in games played between the Vanderbilt Commodores vs Saint Mary’s Gaels

A summary that ties it all together and produces a favorable betting outcome for Vanderbilt Commodores vs Saint Mary’s Gaels game

Saint Mary’s Gaels Preview

The Saint Mary’s Gaels have a 28-5 record this season and are were placed first in the West Coast. The Gaels are coming off a 51-58 loss by Gonzaga in the WCC Final. The Gaels are 14-18 against the spread, and 12-19-1 in over/under.

Offensively, Saint Mary’s is averaging 73.5 points per game, which ranks 166th in the nation. Defensively, they allow 60.7 points per game, which is the 5th-best in the nation. The Gaels shoot with 45.5% from the field (132th), and with 32.3% from beyond the arc (212th). The Gaels shoot with 69.4% from the free-throw line (264th), and are grabbing 36.6 rebounds per game, which is the 16th-best in the nation.

Augustas Marciulionis leads Saint Mary’s in scoring this season, with 14.4 points and a team-high 6.1 assists, while Paulius Murauskas adds 12.8 points and a team-high 8.1 rebounds per game.

Vanderbilt Commodores Preview

The Vanderbilt Commodores have a 20-12 record this season and were placed 12th in the SEC. Vanderbilt is coming off a 72-79 loss by Texas in the first round of the SEC tournament. The Commodores are 18-14 against the spread, and 16-15-1 in over/under.

Offensively, Vanderbilt is averaging 79.6 points per game, which is 49th in the nation. Defensively, they are allowing 74.8 points per game (261st). The Commodores shoot with 45.1% from the field (158th), and with 32.5% from beyond the arc (258th). The Commodores shoot with 74.7% from the free throw line (86th), and are grabbing 31.5 rebounds per game (206th).

Jason Edwards leads Vanderbilt scoring this season, with an average of 17 points, while Tyle Nickel adds 10.5 points per game.

Why the Saint Mary’s Gaels will win

Why the Vanderbilt Commodores will win

Total Points Facts

Matchup/League Facts

Vanderbilt Commodores vs Saint Mary’s Gaels Prediction

Vanderbilt is 3-1 in their four meetings against Saint Mary’s, and are 3-1 against the spread. In their most recent meeting back in 2022, Saint Mary’s won 75-65 on the road, covering the spread.

In this Vanderbilt Commodores vs Saint Mary’s Gaels Prediction, Saint Mary’s is coming as -4-point favorites. Saint Mary’s is rightfully favored, as they have a better record this season, and have been one of the best road teams in the nation with an almost perfect 9-1 record, while Vanderbilt has only 3 wins away from home.

Saint Mary’s is 8-1 in their last 9 games, but 0-4 against the spread in their last 4, while Vandy is 3-6 in their last 9 games and 0-3 against the spread. The Commodores are not in good enough form to keep this one close, so I will take the Saint Mary’s Gaels and lay the -4.5 points in this one.

Nikos Lagouretos's Pick: Saint Mary's Gaels -4.5

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