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Arizona Diamondbacks vs Minnesota Twins Prediction 9/13/2025 Today’s MLB Picks

Sep 10, 2025; Anaheim, California, USA;  Minnesota Twins designated hitter Byron Buxton (25) hits a two-run home run during the sixth inning against the Los Angeles Angels at Angel Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

Sep 10, 2025; Anaheim, California, USA; Minnesota Twins designated hitter Byron Buxton (25) hits a two-run home run during the sixth inning against the Los Angeles Angels at Angel Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

MATCHUP Diamondbacks Arizona Twins Minnesota
Team Records 74-75 65-83
Where Target Field, Minneapolis, Minnesota
When Saturday, September 13, 2025
Time 07:10 PM EDT
TV Twins.TV

The Arizona Diamondbacks and the Minnesota Twins meet Saturday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Diamondbacks vs. Minnesota Twins prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Ryne Nelson for the start here and Nelson is 7-3 with a 3.48 ERA and 118 strikeouts this season. In his career, Nelson is 0-2 with a 16.20 ERA and 8 strikeouts against the Twins. Joe Ryan will get the nod for the Twins and is 13-8 with a 3.32 ERA and 176 strikeouts this season. This will be Ryan’s second career start against the Diamondbacks.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to rebound from a 9-8 loss at the hands of the Twins in Friday’s series opener to drop to 73-75 this season. After this series, the Diamondbacks will make the trip home for a series rematch with the San Francisco Giants.

Diamondbacks Drop 4 Of Last 5

Corbin Carroll has 131 hits with 30 home runs, 74 RBIs, 16 triples and 29 doubles this season. Carroll also has a team-high 26 stolen bases and Geraldo Perdomo has 24 stolen bases as well as 17 home runs and 91 RBIs with a team-high 151 hits this season. Ketel Marte’s added 25 home runs and 64 RBIs as well on the year and Lourdes Gurriel has 124 hits with 24 doubles, 19 home runs and 80 RBIs.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to add on to their win over the Diamondbacks from Friday’s clash to improve to 65-82 this season. After this series, the Twins will welcome the New York Yankees to town for a series.

Twins Trying To Play Spoiler

Byron Buxton has 116 hits along with 18 doubles, a team-high 30 home runs and 74 RBIs with 22 stolen bases and 7 triples while Trevor Larnach’s chipped in 117 hits with 20 doubles, 16 home runs and 57 RBIs as well this season. Brooks Lee has contributed 104 hits with 14 doubles, 14 home runs and 57 RBIs and Matt Wallner has 21 homers and 39 RBIs as well. 

Arizona Diamondbacks @ Minnesota Twins Betting Trends: September 13, 2025

Why the Minnesota Twins will win

Why the Arizona Diamondbacks will win

Total Runs Facts

Minnesota Twins Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Matchup/League Facts

Arizona Diamondbacks vs. Minnesota Twins Prediction

I’m on the Diamondbacks here. I still think that Arizona is just the far superior batting lineup offensively especially after all of the offloading that Minnesota did at the trade deadline. I know that the Twins won’t lose every game, and Ryan is still supposed to be Minnesota’s ace, but he’s been shaky at best as of late and I think Arizona gets some revenge here. Give me the Diamondbacks here.

Chris Ruffolo's Pick: Arizona -105

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