| MATCHUP | Diamondbacks Arizona | Giants San Francisco |
|---|---|---|
| Team Records | 73-74 | 74-72 |
| Where | Oracle Park, San Francisco, California | |
| When | Wednesday, September 10, 2025 | |
| Time | 03:45 PM EDT | |
| TV | NBC Sports BA | |
The Arizona Diamondbacks and San Francisco Giants meet Wednesday in MLB action at Oracle Park. Here’s a Arizona Diamondbacks vs San Francisco Giants Prediction. This article will include a Arizona Diamondbacks vs San Francisco Giants Pick.
Arizona Diamondbacks Betting Preview
The Arizona Diamondbacks are 72-74 on the year and play the Twins, Giants, and Phillies next. The Arizona Diamondbacks are batting .250 on the season, have a .329 OBP, and a .429 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.48 ERA and a 1.32 WHIP. Geraldo Perdomo leads the Arizona Diamondbacks with 150 hits and 91 RBI, while Corbin Carroll and Lourdes Gurriel Jr. have combined for 255 hits and 124 RBI.
Eduardo Rodriguez gets the ball for the Arizona Diamondbacks, and he is 7-8 with a 5.22 ERA and 124 strikeouts this season. Rodriguez is 1-1 with a 6.14 ERA and 22 strikeouts in his career against the San Francisco Giants.
San Francisco Giants Betting Preview
The San Francisco Giants are 74-71 on the year and play the Dodgers, Diamondbacks, and Dodgers next. The San Francisco Giants are batting .239 on the season, have a .314 OBP, and a .393 slugging percentage. The San Francisco Giants pitching staff has a 3.75 ERA and a 1.29 WHIP. Heliot Ramos leads the San Francisco Giants with 146 hits and 61 RBI while Jung Hoo Lee and Willy Adames have combined for 261 hits and 132 RBI.
Carson Seymour gets the ball for the San Francisco Giants, and he is 1-2 with a 4.25 ERA and 20 strikeouts this season. This will be Seymour’s second career game against the Arizona Diamondbacks.
Arizona Diamondbacks @ San Francisco Giants Betting Trends: September 10, 2025
- Probable Starting Pitcher: Carson Seymour Record this season: 1-2 ERA: 4.25
- Home Record: 0-2
- Last 5 against Diamondbacks: 0-0
Why the San Francisco Giants will win
- The Giants have won 11 of their last 12 home games against NL West opponents that held a losing record.
- The Diamondbacks have lost each of their last six day games against National League opponents following a road loss.
- The Giants have covered the run line in seven of their last eight games as favorites.
- The Diamondbacks have failed to cover the run line in seven of their last eight games at Oracle Park against NL West opponents that held a winning record.
- The Diamondbacks have trailed after 5 innings in three of their last four road day games.
- Probable Starting Pitcher: Eduardo Rodriguez Record this season: 7-8 ERA: 5.22
- Road Record: 5-6
- Last 5 against Giants: 1-1
Why the Arizona Diamondbacks will win
- The Diamondbacks have won seven of their last 10 games as underdogs.
- The Giants have lost each of their last four Wednesday games as home favorites.
- The Giants have failed to cover the run line in six of their last seven games as home favorites against National League opponents following a home win.
- The underdogs have covered the run line in 20 of the Diamondbacks’ last 24 games.
- The Giants have trailed after 5 innings in four of their last five day games at Oracle Park against NL West opponents.
Total Runs Facts
- Seven of the Giants’ last eight home games after playing the previous day have gone OVER the total runs line.
- Each of the Diamondbacks’ last three games have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Giants’ last seven games at Oracle Park.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Diamondbacks’ last six day games.
Arizona Diamondbacks Player Prop Facts
- Ketel Marte ranks 6th amongst qualified players for On Base Percentage (.388) this season.
Matchup/League Facts
- The Giants rank 27th in the league for doubles this season (214).
- The Giants rank T4th in the league for triples this season (26).
- The Diamondbacks rank 2nd in the league for slugging percentage this season (.435).
- The Diamondbacks rank T4th in the league for runs scored this season (716).
Arizona Diamondbacks vs San Francisco Giants Prediction
The Diamondbacks aren’t having the best week in the world, and I doubt things improve with Rodriguez on the mound. Rodriguez has a 5.22 ERA and 1.60 WHIP on the season, and he has a 5.17 ERA and .308 allowed batting average in 69.2 road innings. Seymour has had his ups and downs his rookie season, but the Giants as a team have caught fire over the last couple of weeks and find themselves in the thick of the wild card race. This is a spot where you just ride the hot hand and hope tickets keep cashing. Give me the Giants.