Atlanta Braves vs Detroit Tigers Prediction 9/21/2025 Today’s MLB Picks

The Atlanta Braves and Detroit Tigers meet Sunday in MLB action at Comerica Park. Here’s a Atlanta Braves vs Detroit Tigers Prediction. This article will include a Atlanta Braves vs Detroit Tigers Pick.

Atlanta Braves Betting Preview

The Atlanta Braves are 72-83 on the year and play the Nationals and Pirates next. The Atlanta Braves are batting .245 on the season, have a .319 OBP, and a .397 slugging percentage. The Atlanta Braves pitching staff has a 4.39 ERA and a 1.30 WHIP. Matt Olson leads the Atlanta Braves with 166 hits and 93 RBI, while Ozzie Albies and Michael Harris II have combined for 283 hits and 152 RBI.

Spencer Strider gets the ball for the Atlanta Braves, and he is 6-13 with a 4.64 ERA and 120 strikeouts this season. This will be Strider’s second career game against the Detroit Tigers.

Detroit Tigers Betting Preview

The Detroit Tigers are 85-70 on the year and play the Guardians and Red Sox next. The Detroit Tigers are batting .247 on the season, have a .316 OBP, and a .417 slugging percentage. The Detroit Tigers pitching staff has a 3.97 ERA and a 1.25 WHIP. Riley Greene leads the Detroit Tigers with 149 hits and 108 RBI while Spencer Torkelson and Gleyber Torres have combined for 263 hits and 151 RBI.

Casey Mize gets the ball for the Detroit Tigers, and he is 14-5 with a 3.88 ERA and 126 strikeouts this season. This will be Mize’s second career game against the Atlanta Braves.

Atlanta Braves @ Detroit Tigers Betting Trends: September 21, 2025

• Probable Starting Pitcher: Casey Mize      Record this season: 14-5      ERA: 3.88
• Home Record: 8-1
• Last 5 against Braves: 0-1

Why the Detroit Tigers will win

• The Braves have trailed after 5 innings in three of their last four day games against AL Central opponents that held a winning record.

• Probable Starting Pitcher: Spencer Strider      Record this season: 6-13      ERA: 4.64
• Road Record: 3-6
• Last 5 against Tigers: 1-0

Why the Atlanta Braves will win

• The underdogs have won each of the Tigers’ last six games at Comerica Park.
• The Tigers have lost eight of their last nine games as favorites.
• The Braves have covered the run line in each of their last 11 road games after playing the previous day.
• The Tigers have failed to cover the run line in each of their last six home games.
• The Tigers have trailed after 3 innings in three of their last four home games.
• The Tigers have trailed after 5 innings in four of their last five home games.

Total Runs Facts

• Six of the Braves’ last seven games have gone OVER the total runs line.
• Four of the Tigers’ last five games against National League opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Braves’ last six games as underdogs.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Tigers’ last six games as home favorites against National League opponents.

Detroit Tigers Player Prop Facts

• Spencer Torkelson has hit a home run in four of the Tigers’ last five home games against the Braves.
• Spencer Torkelson has recorded at least one hit in each of his last six home appearances against NL East opponents.
• Casey Mize has recorded a win in six of his last seven appearances at Comerica Park against opponents that held a losing record.
• Riley Greene ranks T10th in the league in Home Runs (34) this season.

Atlanta Braves Player Prop Facts

• Ronald Acuna Jr. has hit a home run in three of the Braves’ last four road games against the Tigers.
• Spencer Strider has recorded seven or more strikeouts in four of his five previous road appearances against AL opponents that held a winning record.
• Ozzie Albies has recorded at least one hit in each of the Braves’ last seven games against the Tigers.
• Matt Olson ranks 10th in the league in Hits (166) this season.

Matchup/League Facts

• The Tigers rank 26th in the league for strikeouts against this season (1374).
• The Tigers rank 9th in the league for runs scored this season (741).
• The Braves rank T23rd in the league for doubles this season (234).
• The Braves rank 22nd in the league for ERA this season (4.39).

Atlanta Braves vs Detroit Tigers Prediction

The Braves have nothing to play for, but they’ve put together a hell of a week in the spoiler role, and Strider has allowed 18 hits and 7 runs in his last 25 innings. Mize is having a good year, especially at home where he has a 3.59 ERA and .255 allowed batting average, but the Tigers have one win since September 11. The Tigers are the better team and should win, but the value is with the Braves with how this week has played out.

Randy Chambers's Pick: Atlanta Braves