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Baltimore Orioles vs Toronto Blue Jays Prediction 9/12/2025 Today’s MLB Picks

Sep 11, 2025; Toronto, Ontario, CAN; Toronto Blue Jays first baseman Vladimir Guerrero Jr. (27) gets Houston Astros center fielder Mauricio Dubon (not pictured) out at first base during the sixth inning at Rogers Centre. Mandatory Credit: John E. Sokolowski-Imagn Images

Sep 11, 2025; Toronto, Ontario, CAN; Toronto Blue Jays first baseman Vladimir Guerrero Jr. (27) gets Houston Astros center fielder Mauricio Dubon (not pictured) out at first base during the sixth inning at Rogers Centre. Mandatory Credit: John E. Sokolowski-Imagn Images

MATCHUP Orioles Baltimore Blue Jays Toronto
Team Records 69-78 85-62
Where Rogers Centre, Toronto, Ontario
When Friday, September 12, 2025
Time 07:07 PM EDT
TV MAS+

The Baltimore Orioles and the Toronto Blue Jays meet Friday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Baltimore Orioles vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

The Baltimore Orioles will send out Trevor Rogers for the start here and is 8-2 with a 1.51 ERA and 87 strikeouts this season. In his career, Rogers is 0-1 with a 4.50 ERA and 8 strikeouts against Toronto. Chris Bassitt will start this one for Toronto and is 11-8 with a 3.97 ERA and 157 strikeouts this season. In his last five starts against Baltimore, Bassitt is 2-3 with a 6.39 ERA and 30 strikeouts.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to add on to their 3-2 win over the Pittsburgh Pirates last time out to improve to 69-77 this season. After this series, the Orioles will head on the road for a series against the Chicago White Sox.

Orioles Win 3 Straight And 8 Of Their Last 9

Adley Rutschman has 70 hits with 16 doubles, 9 homers and 29 RBIs. Jackson Holliday has 135 hits with 20 doubles, 2 triples, 17 homers and 54 RBIs. Gunnar Henderson has 140 hits with 31 doubles, 5 triples, 16 home runs and 61 RBIs with 22 stolen bases and 128 strikeouts while Holliday has a team-high 128 strikeouts as well this season. 

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to add on to their 6-0 win over the Houston Astros last time out to sit at 84-62 this season. After this series, the Blue Jays will head on the road for a series against the Tampa Bay Rays.

Blue Jays Pushing For Another Series-Opening Win

George Springer has 127 hits and Bo Bichette has 181 hits with Springer adding 27 home runs, a triple, 21 doubles and 72 RBIs while Bichette has 44 doubles, 18 home runs and 93 RBIs. Andres Gimenez has added 60 hits with 8 doubles and 7 home runs and 27 RBIs this season along with 12 stolen bases. Vladimir Guerrero Jr. also has 23 homers, 33 doubles and 79 RBIs while Springer also has a .301 batting average and 91 strikeouts up to this point in the year. Addison Barger’s chipped in 27 doubles with 19 home runs and 65 RBIs and Ernie Clement’s added 28 doubles as part of his 132 hits this season.

Baltimore Orioles @ Toronto Blue Jays Betting Trends: September 12, 2025

Why the Toronto Blue Jays will win

Why the Baltimore Orioles will win

Total Runs Facts

Toronto Blue Jays Player Prop Facts

Baltimore Orioles Player Prop Facts

Matchup/League Facts

Baltimore Orioles vs. Toronto Blue Jays Prediction

I’m on the under here. Toronto really struggled to find early offense in that series against Houston, doing a lot of damage in the later innings against the Astros, but this is an Orioles bullpen that’s been the best in baseball in September so far, and Trevor Rogers could have a strong case to be made as Baltimore’s staff ace so far this season. On the other side, Bassitt’s been outstanding at home this season and the Orioles have had some issues as of late hitting against right-handed pitching. I’ll side with the under in this one.

Chris Ruffolo's Pick: Under 7.5

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