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Boston Red Sox vs Arizona Diamondbacks Prediction 9/7/2025 Today’s MLB Picks

Sep 6, 2025; Phoenix, Arizona, USA;  Boston Red Sox first base Romy Gonzalez (23) slides into third during the fourth inning between the Arizona Diamondbacks and the Boston Red Sox at Chase Field. Mandatory Credit: Arianna Grainey-Imagn Images

Sep 6, 2025; Phoenix, Arizona, USA; Boston Red Sox first base Romy Gonzalez (23) slides into third during the fourth inning between the Arizona Diamondbacks and the Boston Red Sox at Chase Field. Mandatory Credit: Arianna Grainey-Imagn Images

MATCHUP Red Sox Boston Diamondbacks Arizona
Team Records 78-65 72-71
Where Chase Field, Phoenix, Arizona
When Sunday, September 7, 2025
Time 04:10 PM EDT
TV NESN

In this article, we will formulate a Red Sox vs Diamondbacks Prediction for this MLB game on Sunday, September 7th at the Chase Field in the third game of this series, with the Dbacks having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 72-71 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 38-33 home record and are 67-67 in over/under They are coming off a 5-1 home victory over the Red Sox, and are 8-2 in their last 10 games. Under is 6-3-1 in their last 10 games and are playing the Twins and the Giants next.

The Diamondbacks have a .250 batting average this season, .323 OBP and .437 slugging percentage. Arizona’s pitching staff has a 4.43 ERA and 1.32 WHIP. Geraldo Perdomo leads the Diamondbacks with 150 hits, adding a team-high 91 RBI. He is also the team’s best hitter with a .286 batting average. Corbin Carroll leads the team in home runs with 29.

Ryne Nelson (R) is the projected starting pitcher for the Diamondbacks, and he has a 7-3 record, 3.57 ERA and 1.05 WHIP.

Boston Red Sox Preview

The Boston Red Sox have a 78-65 record this season and are sitting on the third place of the AL East. The Red Sox have a 34-37 road record and are 70-70 in over/under. They are coming off a 1-5 road defeat by the Dbacks, and have three consecutive losses. They are 5-2 to the over in their last 7 games and are playing the Athletics and the Yankees next.

The Red Sox have a .254 batting average this season, .324 OBP and .425 slugging percentage. Boston’s pitching staff has a 3.78 ERA and 1.30 WHIP.  Jarren Duran leads the Red Sox with 142 hits, and he is the team’s best hitter, with a .260 batting average. Trevor Story leads the team in RBI, with 88, adding a team-high 23 home runs.

Brayan Bello (R) is the projected starting pitcher for the Red Sox, and he has a 11-6 record, 3.07 ERA and 1.23 WHIP.

Boston Red Sox @ Arizona Diamondbacks Betting Trends: September 7, 2025

Why the Arizona Diamondbacks will win

Why the Boston Red Sox will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Red Sox vs Diamondbacks Prediction

The Dbacks have won their last six head-to-head meetings against the Red Sox, and both teams are tied 3-3 wins in their last 6 meetings in Arizona.

In this Red Sox vs Diamondbacks Prediction, both teams are coming at a pickem price. Both pitchers have been excellent this season, with a combined 6.64 ERA, and their home/away splits are even better, as Nelson has a 2.60 home ERA and Bello a 2.85 road ERA. Both teams are struggling offensively lately, with the Red Sox having just 7 total runs scored in their last 3 games, and the Dbacks having 5 runs or less in five of their last six games. The total is set at 9, and I don’t think there will be 10 runs scored in this game, so take the under in this one.

Nikos Lagouretos's Pick: Under 9

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