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Chicago Cubs vs Atlanta Braves Prediction 9/10/2025 Today’s MLB Picks

Sep 5, 2025; Atlanta, Georgia, USA; Atlanta Braves first baseman Matt Olson (28) hits an RBI single against the Seattle Mariners in the eighth inning at Truist Park. Mandatory Credit: Brett Davis-Imagn Images

Sep 5, 2025; Atlanta, Georgia, USA; Atlanta Braves first baseman Matt Olson (28) hits an RBI single against the Seattle Mariners in the eighth inning at Truist Park. Mandatory Credit: Brett Davis-Imagn Images

MATCHUP Cubs Chicago Braves Atlanta
Team Records 83-63 65-81
Where Truist Park, Atlanta, Georgia
When Wednesday, September 10, 2025
Time 07:15 PM EDT
TV FanDuel SN South

The Chicago Cubs and the Atlanta Braves meet Wednesday in MLB action from Truist Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago Cubs vs. Atlanta Braves prediction.

Starting Pitching Matchup

The Chicago Cubs did not have a starting pitcher confirmed at the time that this article was posted. The Atlanta Braves will trot out Chris Sale for the start here and Sale is 5-4 with a 2.38 ERA and 132 strikeouts this season. In his career, Sale is 3-1 with a 1.00 ERA and 38 strikeouts against the Cubs.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to build on their 6-1 win over Atlanta last time out to sit at 82-63 this season. After this series, the Cubs will head home for a series against the Tampa Bay Rays.

Cubs Snap Three-Game Losing Streak

Ian Happ has 120 hits with 27 doubles, 20 home runs and 66 RBIs. Kyle Tucker has 132 hits including 25 doubles, 4 triples, 22 home runs and 73 RBIs while Seiya Suzuki also has 130 hits with 29 doubles and 27 home runs and 90 RBIs of his own. Pete Crow-Armstrong also has contributed 134 hits, 35 doubles, 4 triples, 28 home runs and 87 RBIs as well this season. Dansby Swanson has added 22 home runs and 71 RBIs, while also having 153 strikeouts and Suzuki has 156 strikeouts so far this season. Crow-Armstrong also has a team-high 34 stolen bases while Nico Hoerner has 24 stolen bases this season. Tucker’s also added 25 stolen bases while Michael Busch has also chipped in 19 doubles, 4 triples, 26 home runs and 76 RBIs this season.

Atlanta Braves Recap

The Atlanta Braves come into this game looking to rebound from their loss at the hands of the Cubs to sit at 65-80 this season. After this series, the Braves will head home for a series against the Houston Astros.

Braves Looking To Bounce Back

Austin Riley has 108 hits including 16 home runs, 54 RBIs and 20 doubles so far this season. Ozzie Albies has 134 hits with 16 home runs and 65 RBIs in addition to 14 stolen bases and Matt Olson has 150 hits with 36 doubles, 23 home runs and 80 RBIs of his own. Marcell Ozuna also has 98 hits with 20 home runs and 62 RBIs. Michael Harris II also has 133 hits with 22 doubles, 6 triples, 17 home runs and 79 RBIs and 15 stolen bases as well and Nick Allen has 8 stolen bases as well this season.

The Chicago Cubs @ Atlanta Braves Betting Trends: September 10, 2025

Why the Atlanta Braves will win

Why the Chicago Cubs will win

Total Runs Facts

Atlanta Braves Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Chicago Cubs vs. Atlanta Braves Prediction

I’m backing the Braves in this one. I just think that the Braves get a strong start from Chris Sale, who has owned the Cubs for the course of his entire career and I think his matchup from a lineup perspective cancels out, so with a clear edge in starting pitching regardless of who the Cubs send out here, I have to roll with Atlanta in this one.

Chris Ruffolo's Pick: Atlanta -165

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