Aug 24, 2025; Phoenix, Arizona, USA; Cincinnati Reds shortstop Elly De La Cruz against the Arizona Diamondbacks at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

Cincinnati Reds vs Los Angeles Dodgers Prediction 8/27/2025 Today’s MLB Picks

Pick details

Cincinnati (68-65) vs Los Angeles (76-57)

August 27, 2025 at 08:40 PM EDT

The Line: Betting Odds: Los Angeles -205 — Over/Under: +8.5

(Get latest betting odds)

The Cincinnati Reds and the Los Angeles Dodgers meet Wednesday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. Los Angeles Dodgers prediction.

Starting Pitching Matchup

The Cincinnati Reds will give the start to Nick Lodolo here and Lodolo is 8-6 with a 3.05 ERA and 124 strikeouts this season. This will be Lodolo’s second career start against the Dodgers. The Los Angeles Dodgers will give the nod to Shohei Ohtani here and Ohtani is 0-1 with a 4.61 ERA and 35 strikeouts this season. In his career, Ohtani is 0-0 with a 4.15 ERA and 6 strikeouts against Cincinnati.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to rebound from a 6-3 loss at the hands of the Dodgers on Tuesday to sit at 68-65 this season. After this series, the Reds will head home for a division series against the St. Louis Cardinals.

Reds Drop 5 Of Last 6

Elly De La Cruz has 135 hits with 19 home runs, 76 RBIs, 25 doubles and 31 stolen bases while TJ Friedl has 121 hits with 18 doubles, 10 home runs and 40 RBIs with 11 stolen bases. Gavin Lux has added 100 hits with 21 doubles and 48 RBIs while Spencer Steer has 15 home runs and 59 RBIs and Matt McLain has added 11 homers, 40 RBIs and 16 stolen bases as well on the year. Jose Trevino’s also chipped in 19 doubles as well this season.

Why the Cincinnati Reds will win

  • The Dodgers have lost each of their last four Wednesday games as favorites.
  • The Reds have won each of their last three Wednesday night games as underdogs against National League opponents.
  • The Reds have covered the run line in seven of their last eight games as underdogs against NL West opponents following a loss.
  • The Dodgers have failed to cover the run line in each of their last seven Wednesday games as favorites.

Cincinnati Reds Player Prop Facts

  • Nick Lodolo has recorded five or more strikeouts in eight of his last nine appearances against opponents that held a winning record.
  • TJ Friedl has recorded at least one hit in each of his last nine appearances with the Reds as road underdogs.
  • Nick Lodolo has recorded a win in three of his last four road appearances against NL West opponents.
  • Miguel Andujar has hit a home run in three of his last eight appearances with the Reds as underdogs against NL opponents.
  • Elly De La Cruz ranks T8th in the league in Steals (31) this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to add on to their win over the Reds from Tuesday to sit at 76-57 this year. After this series, the Dodgers will have a division series against the Arizona Diamondbacks at home.

Dodgers Win Three In A Row

Shohei Ohtani has 138 hits including 17 doubles, 44 home runs, 83 RBIs and 8 triples while Tommy Edman has 69 hits with 12 home runs and 44 RBIs. Michael Conforto has 63 hits with 18 doubles while Teoscar Hernandez has 101 hits with 21 home runs, 24 doubles and 76 RBIs as well this season. Ohtani has a team-high 17 stolen bases while Max Muncy has 10 doubles but also has 73 strikeouts so far this season. Mookie Betts has also chipped in 13 home runs and 57 RBIs as well on the year. Freddie Freeman has also logged 131 hits with a team-high 32 doubles, 16 home runs and 72 RBIs. Andy Pages also has 127 hits with 21 doubles, 21 home runs and 71 RBIs as well this season.

Why the Los Angeles Dodgers will win

    • The Dodgers have won each of their last eight night games against the Reds at Dodger Stadium following a win.
    • The Reds have lost each of their last six night games against National League opponents.
    • The Dodgers have covered the run line in each of their last seven night games against the Reds at Dodger Stadium following a win.
    • The Reds have failed to cover the run line in 10 of their last 11 night games against National League opponents following a road loss.

Los Angeles Dodgers Player Prop Facts

  • Freddie Freeman has recorded a Double in three of the Dodgers’ last four home games against the Reds.
  • Teoscar Hernandez has recorded at least one hit in each of his last 15 appearances with his team as a favorite against the Reds.
  • Tommy Edman has hit a home run in each of his last two appearances in night games against NL Central teams that held a winning record.
  • Shohei Ohtani ranks T2nd in the league in Home Runs (45) this season.

Total Runs Facts

  • Five of the Reds’ last six night games against National League opponents have gone OVER the total runs line.
  • Four of the Dodgers’ last five night games after playing the previous day have gone UNDER the total runs line.

Cincinnati Reds vs. Los Angeles Dodgers Prediction

I’m on the Dodgers here. I get that the plus money with the Reds is tempting considering that Cincinnati is still in a fight for the playoffs, but the Dodgers are just the better team by a fair margin in this series and I think they get the job done here behind Ohtani, who has struggled lately but has been at his best at home this season. Give me the Dodgers.

Chris Ruffolo's Pick: Los Angeles Dodgers -205

Need More? Get Premium Picks

Hot Cappers

Latest Picks & Game Previews

  • Tarleton State vs Army Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Western Michigan vs Michigan State Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Appalachian State vs Charlotte Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Bethune-Cookman vs FIU Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Kennesaw State vs Wake Forest Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Wagner vs Kansas Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Western Illinois vs Illinois Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Georgia Tech vs Colorado Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • Auburn vs Baylor Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025

  • UNLV vs Sam Houston State Prediction 8/29/2025 Today’s College Football Picks

    August 29, 2025