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Cleveland Guardians vs Tampa Bay Rays Prediction 9/6/2025 Today’s MLB Picks

Sep 5, 2025; St. Petersburg, Florida, USA; Tampa Bay Rays shortstop Carson Williams (77) waits for the ball as Cleveland Guardians left fielder Steven Kwan (38) slides into second base for a stolen base in the sixth inning at George M. Steinbrenner Field. Mandatory Credit: Jonathan Dyer-Imagn Images

Sep 5, 2025; St. Petersburg, Florida, USA; Tampa Bay Rays shortstop Carson Williams (77) waits for the ball as Cleveland Guardians left fielder Steven Kwan (38) slides into second base for a stolen base in the sixth inning at George M. Steinbrenner Field. Mandatory Credit: Jonathan Dyer-Imagn Images

MATCHUP Guardians Cleveland Rays Tampa Bay
Team Records 71-70 71-71
Where George M. Steinbrenner Field, Tampa, Florida
When Saturday, September 6, 2025
Time 07:05 PM EDT
TV CLEGuardians.TV

The Cleveland Guardians and Tampa Bay Rays meet Saturday in MLB action at George M. Steinbrenner Field. Here’s a Cleveland Guardians vs Tampa Bay Rays Prediction. This article will include a Cleveland Guardians vs Tampa Bay Rays Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 70-70 on the year and play the Royals, White Sox, and Tigers next. The Cleveland Guardians are batting .224 on the season, have a .294 OBP, and a .369 slugging percentage. The Cleveland Guardians pitching staff has a 3.95 ERA and a 1.32 WHIP. Steven Kwan leads the Cleveland Guardians with 147 hits and 46 RBI, while Jose Ramirez and Kyle Manzardo have combined for 137 hits and 135 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 9-11 with a 4.77 ERA and 136 strikeouts this season. Bibee is 1-2 with a 4.74 ERA and 17 strikeouts in his career against the Tampa Bay Rays.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 71-70 on the year and play the White Sox, Cubs, and Blue Jays next. The Tampa Bay Rays are batting .252 on the season, have a .314 OBP, and a .403 slugging percentage. The Tampa Bay Rays pitching staff has a 3.87 ERA and a 1.21 WHIP. Yandy Diaz leads the Tampa Bay Rays with 153 hits and 76 RBI while Junior Caminero and Brandon Lowe have combined for 256 hits and 177 RBI.

Shane Baz gets the ball for the Tampa Bay Rays, and he is 9-11 with a 4.98 ERA and 156 strikeouts this season. This will be Baz’s second career game against the Cleveland Guardians.

Cleveland Guardians @ Tampa Bay Rays Betting Trends: September 6, 2025

Why the Tampa Bay Rays will win

Why the Cleveland Guardians will win

Total Runs Facts

Tampa Bay Rays Player Prop Facts

Cleveland Guardians Player Prop Facts

Matchup/League Facts

Cleveland Guardians vs Tampa Bay Rays Prediction

Bibee is really having issues this season, which includes an August where he allowed 39 hits and 23 earned runs in 33.2 innings. In 83 road innings, Bibee has a 5.64 ERA and .271 allowed batting average. With that said, Baz hasn’t been much better with his 4.98 ERA and 1.34 WHIP, and in 72.1 home innings, he has a 6.47 ERA and .280 allowed batting average. Two hittable pitchers, we should see some fireworks on Saturday. I’ll take the over in this spot.

Randy Chambers's Pick: Over 8.5

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