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Colorado Rockies vs San Diego Padres Prediction 9/12/2025 Today’s MLB Picks

Sep 11, 2025; San Diego, California, USA; San Diego Padres right fielder Ramon Laureano (5), left, Jackson Merrill (3), center, and  Fernando Tatis Jr. (23) celebrate after the Padres defeated the Colorado Rockies at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

Sep 11, 2025; San Diego, California, USA; San Diego Padres right fielder Ramon Laureano (5), left, Jackson Merrill (3), center, and Fernando Tatis Jr. (23) celebrate after the Padres defeated the Colorado Rockies at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP Rockies Colorado Padres San Diego
Team Records 41-107 80-68
Where Petco Park, San Diego, California
When Friday, September 12, 2025
Time 09:40 PM EDT
TV Padres.TV

The Colorado Rockies and San Diego Padres meet Friday in MLB action at Petco Park. Here’s a Colorado Rockies vs San Diego Padres Prediction. This article will include a Colorado Rockies vs San Diego Padres Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 40-107 on the year and play the Marlins, Angels, and Mariners next. The Colorado Rockies are batting .238 on the season, have a .295 OBP, and a .388 slugging percentage. The Colorado Rockies pitching staff has a 5.98 ERA and a 1.60 WHIP. Hunter Goodman leads the Colorado Rockies with 135 hits and 87 RBI, while Jordan Beck and Brenton Doyle have combined for 241 hits and 105 RBI.

Tanner Gordon gets the ball for the Colorado Rockies, and he is 5-6 with a 6.60 ERA and 46 strikeouts this season. Gordon is 0-1 with a 6.52 ERA and 9 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 80-67 on the year and play the Mets, White Sox, and Brewers next. The San Diego Padres are batting .251 on the season, have a .320 OBP, and a .385 slugging percentage. The San Diego Padres pitching staff has a 3.62 ERA and a 1.20 WHIP. Luis Arraez leads the San Diego Padres with 162 hits and 55 RBI while Manny Machado and Fernando Tatis Jr. have combined for 298 hits and 147 RBI.

JP Sears gets the ball for the San Diego Padres, and he is 8-10 with a 5.01 ERA and 105 strikeouts this season. Sears is 2-0 with a 3.18 ERA and 7 strikeouts in his career against the Colorado Rockies.

Colorado Rockies @ San Diego Padres Betting Trends: September 12, 2025

Why the San Diego Padres will win

Why the Colorado Rockies will win

Total Runs Facts

San Diego Padres Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs San Diego Padres Prediction

Another Rockies game, another chance to fade one of the worst teams in baseball history. I keep saying that, and the Rockies keep losing. In fact, the Rockies haven’t scored in their last two games. The Rockies have scored a combined four runs in their last five games. The Padres have been shaky over the last couple of weeks and Sears isn’t having a great season, but it’s the Rockies. You’ve stacked up a mountain of profit just blindly fading the Rockies this season. Don’t stop now. Give me the Padres and the RL for max betting value.

Randy Chambers's Pick: San Diego Padres

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