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Colorado Rockies vs San Francisco Giants Prediction 9/27/2025 Today’s MLB Picks

Sep 16, 2025; Phoenix, Arizona, USA; San Francisco Giants first baseman Wilmer Flores against the Arizona Diamondbacks at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

Sep 16, 2025; Phoenix, Arizona, USA; San Francisco Giants first baseman Wilmer Flores against the Arizona Diamondbacks at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

MATCHUP Rockies Colorado Giants San Francisco
Team Records 43-118 80-81
Where Oracle Park, San Francisco, California
Time Sep 27th, 8:05 PM Z
TV MLB.TV

The Colorado Rockies and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Rockies vs. San Francisco Giants prediction.

Starting Pitching Matchup

The Colorado Rockies will send out Kyle Freeland here and Freeland is 5-16 with a 5.00 ERA and 120 strikeouts this season. In his last five starts against the Giants, Freeland is 1-2 with a 6.55 ERA and 22 strikeouts. Justin Verlander will start this one for the Giants and is 3-11 with a 3.88 ERA and 130 strikeouts this season. In his last five starts against the Rockies, Verlander is 2-1 with a 3.73 ERA and 31 strikeouts. 

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their series-opening 6-3 loss at the hands of the Giants to fall to 43-117 this season.

Rockies Trying To Salvage Something From Lose Season

Hunter Goodman leads the Rockies with 147 hits including 27 doubles, 5 triples, 30 home runs and 90 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 132 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 15 home runs, 27 doubles, 52 RBIs, 5 triples and 19 stolen bases. Brenton Doyle has 113 hits with 21 doubles, 14 home runs, 56 RBIs and 17 stolen bases. Mickey Moniak has 117 hits with 20 doubles, 8 triples and 24 home runs with 68 RBIs. Tyler Freeman also has 106 hits with 20 doubles and 18 stolen bases so far this season.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to add on to their win over Colorado from Friday’s matchup to sit at 79-81 on the year.

Giants Looking To Finish Season On A Run

Jung Hoo Lee has 143 hits including a team-high 31 doubles along with 11 triples, 8 home runs and 53 RBIs with 10 stolen bases while Heliot Ramos has 157 hits with 24 doubles, 20 home runs and 66 RBIs. Wilmer Flores also has 16 home runs and 71 RBIs while Tyler Fitzgerald has 9 stolen bases as well on the year. Matt Chapman also has 103 hits with 21 home runs and 61 RBIs along with 22 doubles and Willy Adames has 131 hits with 22 doubles, 28 home runs and 84 RBIs of his own this season. 

Colorado Rockies @ San Francisco Giants Betting Trends: September 27, 2025

Why the San Francisco Giants will win

Why the Colorado Rockies will win

Total Runs Facts

San Francisco Giants Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs. San Francisco Giants Prediction

I’m on the Rockies here. I know it’s still expecting something from the worst team in baseball, but the thing is that I have a hard time laying this kind of price with Justin Verlander and the Giants who still have a horrid win percentage in his team starts this season. I just think it’s worth taking a shot on Colorado and hte hefty plus money here. Give me the Rockies.

Chris Ruffolo's Pick: Colorado +195

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