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Houston Astros vs Athletics Prediction 9/25/2025 Today’s MLB Picks

Sep 24, 2025; West Sacramento, California, USA; Houston Astros shortstop Carlos Correa (1) hits a double against the Athletics in the ninth inning at Sutter Health Park. Mandatory Credit: Cary Edmondson-Imagn Images

Sep 24, 2025; West Sacramento, California, USA; Houston Astros shortstop Carlos Correa (1) hits a double against the Athletics in the ninth inning at Sutter Health Park. Mandatory Credit: Cary Edmondson-Imagn Images

MATCHUP Astros Houston Athletics Oakland
Team Records 84-74 75-83
Where Sutter Health Park, Sacramento, California
Time Sep 23rd, 7:35 PM Z
TV MLB.TV
The Houston Astros and Athletics meet Thursday in MLB action at Sutter Health Park. Here’s a Houston Astros vs Athletics Prediction. This article will include a Houston Astros vs Athletics Pick.

Houston Astros Betting Preview


The Houston Astros are 84-74 on the year and play the Angels next. The Houston Astros are batting .250 on the season, have a .315 OBP, and a .396 slugging percentage. The Houston Astros pitching staff has a 3.88 ERA and a 1.22 WHIP. Jose Altuve leads the Houston Astros with 153 hits and 75 RBI, while Jeremy Pena and Christian Walker have combined for 284 hits and 144 RBI.

Framber Valdez gets the ball for the Houston Astros, and he is 12-11 with a 3.75 ERA and 177 strikeouts this season. Valdez is 7-4 with a 2.66 ERA and 88 strikeouts in his career against the Athletics.

Athletics Betting Preview


The Athletics are 75-83 on the year and play the Royals next. The Athletics are batting .253 on the season, have a .318 OBP, and a .432 slugging percentage. The Athletics pitching staff has a 4.66 ERA and a 1.36 WHIP. Brent Rooker leads the Athletics with 163 hits and 89 RBI while Tyler Soderstrom and Jacob Wilson have combined for 304 hits and 153 RBI.

J.T. Ginn gets the ball for the Athletics, and he is 4-6 with a 4.57 ERA and 95 strikeouts this season. Ginn is 1-0 with a 1.69 ERA and 9 strikeouts in his career against the Houston Astros.

Houston Astros @ Athletics Betting Trends: September 25, 2025


Why the Athletics will win

Why the Houston Astros will win

Total Runs Facts

Matchup/League Facts

Houston Astros vs Athletics Prediction


The Astros looked like a team that was going to win the AL West to falling out of the wild card race. The Astros are in trouble. And while you’d think they could turn it around against the Athletics, Valdez has allowed 25 hits and 19 earned runs in his last 20.2 innings. In 90.2 road innings, Valdez has a 4.96 ERA and .254 allowed batting average. The Athletics are playing until the finish line, and Ginn has allowed 12 hits and 3 runs in his last 15.1 innings. I’m going to side with the Athletics, as the Astros picked the wrong week to play poorly.

Randy Chambers's Pick: Athletics

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