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Kansas City Royals vs Cleveland Guardians Prediction 9/11/2025 Today’s MLB Picks

Sep 10, 2025; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) hits a double in the seventh inning against the Kansas City Royals at Progressive Field. Mandatory Credit: David Richard-Imagn Images

Sep 10, 2025; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) hits a double in the seventh inning against the Kansas City Royals at Progressive Field. Mandatory Credit: David Richard-Imagn Images

MATCHUP Royals Kansas City Guardians Cleveland
Team Records 74-73 75-71
Where Progressive Field, Cleveland, Ohio
When Thursday, September 11, 2025
Time 07:15 PM EDT
TV FOX

In this article, we will formulate a Royals vs Guardians Prediction for this MLB game on Thursday, September 11th at the Progressive Field in the 4th game of this series, with the Royals having the 2-1 lead. Let’s take a look at the prediction for this MLB matchup.

Cleveland Guardians Preview

The Cleveland Guardians have a 74-71 record this season and are sitting on the third place of the AL Central. The Guardians have a 37-34 home record and are 67-73 in over/under. They are coming off a 3-4 home defeat by the Royals, that ended their five-game winning streak. Under is 4-1 in their last 5 games and are playing the Tigers and the White Sox next.

The Guardians have a .225 batting average this season, .297 OBP and .370 Slugging percentage. Cleveland’s pitching staff has a 3.87 ERA and 1.30 WHIP. Stephen Kwan leads the Guardians with 154 hits, while Jose Ramirez is the team’s best hitter with a .287 batting average. He also leads the team both in RBI, with 76, and in home runs with 28.

Gavin Williams (R) is the projected starting pitcher for the Guardians, and he has a 10-5 record, 3.17 ERA and 1.29 WHIP.

Kansas City Royals Preview

The Kansas City Royals have a 74-72 record this season and are sitting on the second place of the AL Central. The Royals have a 34-37 road record and are 61-84 in over/under. They are coming off a 4-3 road victory over the Guardians, that ended their three-game losing streak. Under is 8-2 in their last 10 games and are playing the Mariners and the Blue Jays next.

The Royals have a .244 batting average this season, .305 OBP and .390 Slugging percentage. Kansas’ pitching staff has a 3.67 ERA and 1.25 WHIP. Bobby Witt Jr. leads the Royals with 163 hits, and he is the team’s best hitter with a .295 batting average. Vinnie Pasquantino leads the team in RBI, with 100, and a team-high 29 home runs.

Stephen Kolek (R) is the projected starter for the Royals, and he has a 5-5 record, 3.88 ERA and 1.24 WHIP.

Kansas City Royals @ Cleveland Guardians Betting Trends: September 11, 2025

Why the Cleveland Guardians will win

Why the Kansas City Royals will win

Total Runs Facts

Cleveland Guardians Player Prop Facts

Kansas City Royals Player Prop Facts

Matchup/League Facts

Royals vs Guardians Prediction

The Guardians are 6-4 in their last 10 meetings against the Royals, and are 4-2 in their last 6 meetings in Cleveland. Under is 3-1 in their last 4 meetings.

In this Royals vs Guardians Prediction, the Guardians are coming as -140 home favorites. This is as balanced of a matchup as it gets, as both pitchers have similar ERA’s and WHIP, and they both have better home/away splits. Williams has been better at home, with a 3.00 ERA, while Kolen has been better on the road, with a 2.41 ERA. They are both coming into this matchup in good form, and both offenses are ranking on the bottom-4 of the league. The previous two games of this series had 7 and 2 total runs, and I expect another low-scoring affair today. Take the under 7.5 runs in this one.

Nikos Lagouretos's Pick: Under 7.5

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