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Kansas City Royals vs Los Angeles Angels Prediction 9/24/2025 Today’s MLB Picks

Aug 9, 2025; Detroit, Michigan, USA;  Los Angeles Angels starting pitcher Yusei Kikuchi (16) throws a pitch against the Detroit Tigers in the second  inning at Comerica Park. Mandatory Credit: Lon Horwedel-Imagn Images

Aug 9, 2025; Detroit, Michigan, USA; Los Angeles Angels starting pitcher Yusei Kikuchi (16) throws a pitch against the Detroit Tigers in the second inning at Comerica Park. Mandatory Credit: Lon Horwedel-Imagn Images

MATCHUP Royals Kansas City Angels Los Angeles
Team Records 79-79 71-87
Where Angel Stadium, Anaheim, California
When Wednesday, September 24, 2025
Time 09:38 PM EDT
TV MLB.TV

In this article, we will formulate a Royals vs Angels Prediction for this MLB game on Wednesday, September 24th at the Angel Stadium in the second game of this series, with the Royals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 70-87 record this season and are sitting on the 4th place of the AL West. The Angels have a 37-39 home record and 86-68 in over/under They are coming off a 4-8 home defeat by the Royals, and are 1-10 in their last 11 games. They are playing the Astros next.

The Angels have a .226 batting average this season, .299 OBP and .398 Slugging percentage. LA’s pitching staff has a 4.88 ERA and 1.44 WHIP. Taylor Ward leads the Angels with 130 hits, while Nolan Schanuel is the team’s best hitter with a .268 batting average. Taylor Ward leads the team with 102 RBI, while Jo Adell adds a team-high 36 home runs.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 6-11 record, 4.05 ERA and 1.45 WHIP.

Kansas City Royals Preview

The Kansas City Royals have a 79-78 record this season and are sitting on the second place of the AL Central. The Royals have a 36-40 road record and are 69-87 in over/under. They are coming off an 8-4 road victory over the Angels, and are 3-1 in their last 4 games. Over is 8-2 in their last 10 games and are playing the Athletics next.

The Royals have a .248 batting average this season, .309 OBP and .397 Slugging percentage. Kansas’ pitching staff has a 3.76 ERA and 1.25 WHIP. Bobby Witt Jr. leads the Royals with 176 hits, and he is the team’s best hitter with a .293 batting average. Vinnie Pasquantino leads the team in RBI, with 108, and a team-high 31 home runs.

Stephen Kolek (R) is the projected starter for the Royals, and he has a 5-6 record, 3.54 ERA and 1.14 WHIP.

Kansas City Royals @ Los Angeles Angels Betting Trends: September 24, 2025

Why the Los Angeles Angels will win

Why the Kansas City Royals will win

Total Runs Facts

Los Angeles Angels Player Prop Facts

Kansas City Royals Player Prop Facts

Matchup/League Facts

Royals vs Angels Prediction

Both teams are tied 2-2 wins in their last 4 head-to-head meetings, but the Royals are 4-1 in their last 5 visits in Los Angeles. Under is 6-2 in their last 8 meetings.

In this Royals vs Angels Prediction, the Angels are coming as -125 home favorites. The Royals are technically eliminated from the playoffs, and are facing an Angels team with Kikuchi on the mound, who has been significantly better at home, with a 3.00 ERA. But Kolek has also been better on the road, with a 2.31 road ERA, and coming in excellent form, with a 1.91 ERA in his last 5 starts. Kikuchi has been terrible lately, having lost his last 5 starts with an 8.10 ERA, and the Angels have the third-worst bullpen in baseball. Take the Kansas City Royals on the moneyline for plus money in this one.

Nikos Lagouretos's Pick: Kansas City Royals ML

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