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Kansas City Royals vs Oakland Athletics Prediction 9/26/2025 Today’s MLB Picks

Sep 14, 2025; Philadelphia, Pennsylvania, USA; Kansas City Royals starting pitcher Noah Cameron (65) throws a pitch against the Philadelphia Phillies in the first inning at Citizens Bank Park. Mandatory Credit: Kyle Ross-Imagn Images

Sep 14, 2025; Philadelphia, Pennsylvania, USA; Kansas City Royals starting pitcher Noah Cameron (65) throws a pitch against the Philadelphia Phillies in the first inning at Citizens Bank Park. Mandatory Credit: Kyle Ross-Imagn Images

MATCHUP Royals Kansas City Athletics Oakland
Team Records 80-79 75-84
Where Sutter Health Park, Sacramento, California
Time Sep 27th, 2:05 AM Z
TV MLB.TV

In this article, we will formulate a Royals vs Athletics Prediction for this MLB game on Friday, September 26th at the Sutter Health Park in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 75-84 record this season and are sitting on the last place of the AL West. The Athletics have a 35-43 home record and are 77-75 in over/under. They are coming off a 5-11 home defeat the Astros, that ended their two-game winning streak. Under is 6-3-1 in their last 10 games.

The Athletics have a .254 batting average this season, .318 OBP and .433 Slugging percentage. Athletics’ pitching staff has a 4.70 ERA and 1.36 WHIP. Brent Rooker leads the Athletics with 163 hits, while Jacob Wilson is the team’s best hitter with a .313 batting average. Tyler Soderstrom adds a team-high 93 RBI, while Nick Kurtz adds a team-high 35 home runs. 

The Athletics have not announced a starting pitcher for this matchup.

Kansas City Royals Preview

The Kansas City Royals have an 80-79 record this season and are sitting on the second place of the AL Central. The Royals have a 37-41 road record and are 70-88 in over/under. They are coming off a 9-4 road victory over the Angels, and are 4-2 in their last 6 games. Over is 7-3 in their last 10 games.

The Royals have a .247 batting average this season, .309 OBP and .396 Slugging percentage. Kansas’ pitching staff has a 3.75 ERA and 1.24 WHIP. Bobby Witt Jr. leads the Royals with 180 hits, and he is the team’s best hitter with a .296 batting average. Vinnie Pasquantino leads the team in RBI, with 111, and a team-high 32 home runs.

Noah Cameron (L) is the projected starter for the Royals, and he has a 9-7 record, 2.90 ERA and 1.08 WHIP.

Kansas City Royals @ Athletics Betting Trends: September 26, 2025

Why the Athletics will win

Why the Kansas City Royals will win

Total Runs Facts

Athletics Player Prop Facts

Kansas City Royals Player Prop Facts

Matchup/League Facts

Royals vs Athletics Prediction

The Athletics are 5-1 in their last 6 meetings against the Royals, and are 2-1 in their last 3 home meetings. Under is 7-3 in their last 10 meetings.  

In this Royals vs Athletics Prediction, the Royals are coming as -125 road favorites. Both teams have nothing to play for, but the Royals were fighting for a wild card spot until a few days ago. They are now putting their ace on the mound in Noah Cameron, who has been elite this season and better on the road. Kansas City also has a superior bullpen to back him up, so I expect them to take care of business on the road in this one.

Nikos Lagouretos's Pick: Royals -125

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