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Los Angeles Angels vs Colorado Rockies Prediction 9/20/2025 Today’s MLB Picks

Sep 19, 2025; Denver, Colorado, USA; Los Angeles Angels third baseman Yoan Moncada (5) hits a sacrifice fly RBI in the fifth inning against the Colorado Rockies at Coors Field. Mandatory Credit: Isaiah J. Downing-Imagn Images

Sep 19, 2025; Denver, Colorado, USA; Los Angeles Angels third baseman Yoan Moncada (5) hits a sacrifice fly RBI in the fifth inning against the Colorado Rockies at Coors Field. Mandatory Credit: Isaiah J. Downing-Imagn Images

MATCHUP Angels Los Angeles Rockies Colorado
Team Records 70-85 42-113
Where Coors Field, Denver, Colorado
When Saturday, September 20, 2025
Time 08:10 PM EDT
TV MLB.TV

In this article, we will formulate an Angels vs Rockies Prediction for this MLB game on Saturday, September 209th at the Coors Field in the second game of this series, with the Rockies having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Colorado Rockies Preview

The Colorado Rockies have a 42-112 record this season and are sitting on the last place of the NL West. The Rockies have a 24-55 home record and are 69-80 in over/under. They are coming off a 7-6 home victory over the Angels, that ended their five-game losing streak. Over is 6-0 in their last 6 games, and are playing the Mariners and the Giants next.

The Rockies have a .240 batting average this season, .296 OBP and .391 Slugging percentage. Colorado’s pitching staff has a 6.04 ERA and 1.60 WHIP. Hunter Goodman leads the Rockies with 142 hits, also leading the team both in RBI, with 88, and in home runs, with 30. He is also the team’s best hitter with a .280 batting average.

German Marquez (R) is the projected starting pitcher for the Rockies, and he has a 3-14 record, 6.73 ERA and 1.77 WHIP.

Los Angeles Angels Preview

The Los Angeles Angels have a 69-85 record this season and are sitting on the 4th place of the AL West. The Angels have a 32-47 road record and 85-66 in over/under They are coming off a 6-7 road defeat by the Rockies, and have seven consecutive losses. Over is 10-3 in their last 13 games and are playing the Astros and the Royals next.

The Angels have a .227 batting average this season, .300 OBP and .399 Slugging percentage. LA’s pitching staff has a 4.90 ERA and 1.45 WHIP. Zach Neto leads the Angels with 129 hits, while Nolan Schanuel is the team’s best hitter with a .268 batting average. Taylor Ward leads the team with 100 RBI, while Jo Adell adds a team-high 36 home runs.

Kyle Hendricks (L) is the projected starting pitcher for the Angels, and he has a 7-10 record, 5.01 ERA and 1.32 WHIP.

Los Angeles Angels @ Colorado Rockies Betting Trends: September 20, 2025

Why the Colorado Rockies will win

Why the Los Angeles Angels will win

Total Runs Facts

Colorado Rockies Player Prop Facts

Los Angeles Angels Player Prop Facts

Matchup/League Facts

Angels vs Rockies Prediction

The Rockies are 4-1 in their last 5 head-to-head meetings the Angels, and are 3-2 in their last 5 meetings in Colorado. Over is 7-3 in their last 10 meetings.

In this Angels vs Rockies Prediction, the Angels are coming as -130 road favorites. I don’t trust either team at this point for the season, as neither is interested to win. Both pitchers have been terrible, with a combined 11.74 ERA, and Hendricks has been even weaker on the road for the Angels, with a 5.78 ERA. Marquez has been absolutely horrendous lately, having lost his last 5 starts with a 12.36 ERA in that span, so I expect fireworks offensively in this game. Take the over 11.5 runs in this one.

Nikos Lagouretos's Pick: Over 11.5

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