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Los Angeles Angels vs Milwaukee Brewers Prediction 9/16/2025 Today’s MLB Picks

Aug 12, 2025; Milwaukee, Wisconsin, USA; Milwaukee Brewers starting pitcher Freddy Peralta (51) throws a pitch in the first inning against the Pittsburgh Pirates at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images

Aug 12, 2025; Milwaukee, Wisconsin, USA; Milwaukee Brewers starting pitcher Freddy Peralta (51) throws a pitch in the first inning against the Pittsburgh Pirates at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images

MATCHUP Angels Los Angeles Brewers Milwaukee
Team Records 69-82 92-59
Where American Family Field, Milwaukee, Wisconsin
When Tuesday, September 16, 2025
Time 07:40 PM EDT
TV FanDuel SN West

In this article, we will formulate an Angels vs Brewers Prediction for this MLB game on Tuesday, September 16th at the American Family Field in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 91-59 record this season and are sitting on the first place of the NL Central. They have a 48-27 home record and are 72-73 in over/under. They are coming off a 2-3 home defeat by the Cardinals, that ended their two-game winning streak. Over is 5-2 in their last 7 games and are playing the Cardinals and the Padres next.

The Brewers have a .260 batting average this season, .333 OBP and .408 Slugging percentage. Milwaukee’s pitching staff has a 3.63 ERA and 1.24 WHIP. Brice Turang leads the Brewers with 156 hits, while Christian Yelich leads the team in RBI, with 96, adding a team-high 28 home runs. Sal Frelick is the team’s best hitter with a .295 batting average.

Freddy Peralta (R) is the projected starting pitcher for the Brewers, and he has a 16-6 record, 2.69 ERA and 1.09 WHIP.

Los Angeles Angels Preview

The Los Angeles Angels have a 69-81 record this season and are sitting on the 4th place of the AL West. The Angels have a 32-43 road record and 82-65 in over/under They are coming off a 2-11 road defeat by the Mariners, and have four consecutive losses. Over is 7-3 in their last 10 games and are playing the Rockies and the Royals next.

The Angels have a .228 batting average this season, .302 OBP and .399 Slugging percentage. LA’s pitching staff has a 4.83 ERA and 1.44 WHIP. Zach Neto leads the Angels with 129 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 98 RBI, while Jo Adell adds a team-high 36 home runs.

Caden Dana (R) is the projected starting pitcher for the Angels, and he has a 0-1 record, 6.32 ERA and 1.60 WHIP.

Los Angeles Angels @ Milwaukee Brewers Betting Trends: September 16, 2025

Why the Milwaukee Brewers will win

Why the Los Angeles Angels will win

Total Runs Facts

Milwaukee Brewers Player Prop Facts

Los Angeles Angels Player Prop Facts

Matchup/League Facts

Angels vs Brewers Prediction

The Brewers are 4-2 in their last 6 meetings against the Angels, but both teams are tied 2-2 wins in their last 4 meetings Milwaukee. Under is 5-1-1 in their last 7 meetings.

In this Angels vs Brewers Prediction, the Brewers are coming as -210 home favorites. The Brewers have a huge pitching advantage in this matchup, as their best pitcher takes the mound, in Freddy Peralta, who has been elite at home, with a 1.72 ERA. Dana is coming off a terrible start, having given up 5 runs to the Twins, and the Angels have the third-worst bullpen ERA in baseball. Milwaukee has the third-best offense in baseball, and I expect them to dominate this game and cover the runline.

Nikos Lagouretos's Pick: Milwaukee Brewers -1.5

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