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Los Angeles Angels vs Seattle Mariners Prediction 9/12/2025 Today’s MLB Picks

Sep 11, 2025; Seattle, Washington, USA; Seattle Mariners catcher Cal Raleigh (29) smears shaving cream on pinch hitter Harry Ford (5) after the Mariners defeated the Los Angeles Angels at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images

Sep 11, 2025; Seattle, Washington, USA; Seattle Mariners catcher Cal Raleigh (29) smears shaving cream on pinch hitter Harry Ford (5) after the Mariners defeated the Los Angeles Angels at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images

MATCHUP Angels Los Angeles Mariners Seattle
Team Records 69-79 79-68
Where T-Mobile Park, Seattle, Washington
When Friday, September 12, 2025
Time 10:10 PM EDT
TV FanDuel SN West

The Los Angeles Angels and Seattle Mariners meet Friday in MLB action at T-Mobile Park. Here’s a Los Angeles Angels vs Seattle Mariners Prediction. This article will include a Los Angeles Angels vs Seattle Mariners Pick.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 69-78 on the year and play the Brewers, Rockies, and Royals next. The Los Angeles Angels are batting .229 on the season, have a .304 OBP, and a .402 slugging percentage. The Los Angeles Angels pitching staff has a 4.79 ERA and a 1.43 WHIP. Zach Neto leads the Los Angeles Angels with 129 hits and 62 RBI, while Nolan Schanuel and Taylor Ward have combined for 243 hits and 146 RBI.

Yusei Kikuchi gets the ball for the Los Angeles Angels, and he is 6-11 with a 4.18 ERA and 163 strikeouts this season. Kikuchi is 1-2 with a 1.29 ERA and 35 strikeouts in his career against the Seattle Mariners.

Seattle Mariners Betting Preview

The Seattle Mariners are 79-68 on the year and play the Royals, Astros, and Rockies next. The Seattle Mariners are batting .243 on the season, have a .319 OBP, and a .414 slugging percentage. The Seattle Mariners pitching staff has a 3.95 ERA and a 1.25 WHIP. Julio Rodriguez leads the Seattle Mariners with 161 hits and 89 RBI while JP Crawford and Randy Arozarena have combined for 274 hits and 123 RBI.

Luis Castillo gets the ball for the Seattle Mariners, and he is 9-8 with a 3.85 ERA and 144 strikeouts this season. Castillo is 5-2 with a 2.97 ERA and 75 strikeouts in his career against the Los Angeles Angels.

Los Angeles Angels @ Seattle Mariners Betting Trends: September 12, 2025

Why the Seattle Mariners will win

Why the Los Angeles Angels will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Los Angeles Angels Player Prop Facts

Matchup/League Facts

Los Angeles Angels vs Seattle Mariners Prediction

It’s hard to find confidence in teams like the Angels this time of year, and Kikuchi has allowed 14 hits and 12 runs in his last 7.2 innings. Kikuchi has allowed 18 runs in his last 11.2 innings. In 77.2 road innings, Kikuchi has a 5.45 ERA and .289 allowed batting average. No, thanks. The Mariners are making their playoff push with a strong week, and Castillo has been great at home with his 2.79 ERA and .206 allowed batting average in 87 innings. The Mariners need to take advantage of series like this to inch closer to the postseason. Give me the M’s at home.

Randy Chambers's Pick: Seattle Mariners

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