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Los Angeles Dodgers vs Arizona Diamondbacks Prediction 9/25/2025 Today’s MLB Picks

Arizona Diamondbacks base runner Corbin Carroll (7) slides back in safely to first base against the Los Angeles Dodgers at Chase Field in Phoenix, on Sept. 24, 2025.

Arizona Diamondbacks base runner Corbin Carroll (7) slides back in safely to first base against the Los Angeles Dodgers at Chase Field in Phoenix, on Sept. 24, 2025.

MATCHUP Dodgers Los Angeles Diamondbacks Arizona
Team Records 90-69 80-79
Where Chase Field, Phoenix, Arizona
Time Sep 25th, 7:40 PM Z
TV MLBN

The Los Angeles Dodgers and the Arizona Diamondbacks meet Thursday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Yoshinobu Yamamoto here and Yamamoto is 11-8 with a 2.58 ERA and 194 strikeouts this season. In his last five starts against the Diamondbacks, Yamamoto is 2-1 with a 2.30 ERA and 36 strikeouts. Zac Gallen will get the start for the Diamondbacks here and is 13-14 with a 4.70 ERA and 172 strikeouts this season. In his last five starts against the Dodgers, Gallen is 1-2 with a 6.23 ERA and 27 strikeouts.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to build on their 5-4 extra innings win over Arizona from Wednesday’s matchup to improve to 89-69 this season. After this series, the Dodgers will head on the road for an interleague series against the Seattle Mariners.

Dodgers Looking To Build Momentum

Shohei Ohtani has 167 hits including 24 doubles, 53 home runs, 99 RBIs and 8 triples. Michael Conforto has 82 hits with 20 doubles while Teoscar Hernandez has 120 hits with 24 home runs, 28 doubles and 85 RBIs as well this season. Ohtani has a team-high 19 stolen bases while Max Muncy has 10 doubles but also has 73 strikeouts so far this season. Mookie Betts has also chipped in 20 home runs and 79 RBIs as well on the year. Freddie Freeman has also logged 158 hits with a team-high 39 doubles, 21 home runs and 85 RBIs. Andy Pages also has 155 hits with 27 doubles, 25 home runs and 82 RBIs as well this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to bounce back from their loss at the hands of the Dodgers last time out, sitting at 80-78 this season. After this series, the Diamondbacks will head on the road for a series against the San Diego Padres.

Diamondbacks Have Three-Game Win Streak Snapped

Corbin Carroll has 143 hits with 31 home runs, 83 RBIs, 17 triples and 31 doubles this season. Carroll also has a team-high 30 stolen bases and Geraldo Perdomo has 26 stolen bases as well as 19 home runs and 97 RBIs with a team-high 166 hits this season. Ketel Marte’s added 26 home runs and 70 RBIs as well on the year and Lourdes Gurriel has 124 hits with 24 doubles, 19 home runs and 80 RBIs.

Los Angeles Dodgers @ Arizona Diamondbacks Betting Trends: September 25, 2025

Why the Arizona Diamondbacks will win

Why the Los Angeles Dodgers will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Los Angeles Dodgers Player Prop Facts

Matchup/League Facts

Los Angeles Dodgers vs. Arizona Diamondbacks Prediction

I’m going to side with Arizona here. I think that both of these starters have a solid outing, and while Arizona’s bullpen has been less trustworthy for much of the season, I still think that the Diamondbacks sense of urgency kicks in here as the Dodgers are almost locked into the 3-seed in the National League. I think Arizona gets another key win in the Wild Card race and gets the job done here. Give me Arizona.

Chris Ruffolo's Pick: Arizona +125

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