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Miami Marlins vs Philadelphia Phillies Prediction 9/23/2025 Today’s MLB Picks

Sep 10, 2025; Philadelphia, Pennsylvania, USA; Philadelphia Phillies pitcher Cristopher Sanchez (61) throws a pitch against the New York Mets during the first inning at Citizens Bank Park. Mandatory Credit: Bill Streicher-Imagn Images

Sep 10, 2025; Philadelphia, Pennsylvania, USA; Philadelphia Phillies pitcher Cristopher Sanchez (61) throws a pitch against the New York Mets during the first inning at Citizens Bank Park. Mandatory Credit: Bill Streicher-Imagn Images

MATCHUP Marlins Miami Phillies Philadelphia
Team Records 77-80 92-65
Where Citizens Bank Park, Philadelphia, Pennsylvania
When Tuesday, September 23, 2025
Time 06:45 PM EDT
TV MLB.TV

In this article, we will formulate a Marlins vs Phillies Prediction for this MLB game on Tuesday, September 23rd at the Citizens Bank Park in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Philadelphia Phillies Preview

The Philadelphia Phillies have a 92-64 record this season and are sitting on the first place of the NL East. They have a 51-24 home record, and are 70-76 in over/under. They are coming off a 2-9 road defeat by the Dbacks, and are 1-3 in their last four games. They are playing the Twins next.

The Phillies have a .260 batting average this season, .330 OBP and .431 Slugging percentage. Philly’s pitching staff has a 3.88 ERA and 1.25 WHIP. Trea Turner leads the Phillies with 179 hits and he is the team’s best hitter, with a .305 batting average. Kyle Schwarber leads the team with 129 RBI and a team-high 53 home runs.

Cristopher Sanchez (L) is the projected starting pitcher for the Phillies, and he has a 13-5 record, 2.66 ERA and 1.10 WHIP.

Miami Marlins Preview

The Miami Marlins have a 76-80 record this season and are sitting on the third place of the NL East. The Marlins have a 40-38 road record and are 79-72 in over/under. They are coming off a 4-2 road victory over the Rangers, and have six consecutive wins. Over is 4-2 in their last 6 games and are playing the Mets next.

The Marlins have a .252 batting average this season, .316 OBP and .397 slugging percentage. Miami’s pitching staff has a 4.63 ERA and 1.30 WHIP.  Xavier Edwards leads the Marlins with 152 hits, and he is the team’s best hitter with a .281 batting average. He also adds a team-high 25 home runs, while Otto Lopez leads the team in RBI, with 77.

Edward Cabrera (R) is the projected starting pitcher for the Marlins, and he has a 7-7 record, 3.57 ERA and 1.21 WHIP.

Miami Marlins @ Philadelphia Phillies Betting Trends: September 23, 2025

Why the Philadelphia Phillies will win

Why the Miami Marlins will win

Total Runs Facts

Philadelphia Phillies Player Prop Facts

Miami Marlins Player Prop Facts

Matchup/League Facts

Marlins vs Phillies Prediction

The Phillies are 4-1 in their last 5 head-to-head meetings against the Marlins, and are 2-1 in their last 3 meetings in Philadelphia. Under is 3-1-1 in their last 5 meetings.

In this Marlins vs Phillies Prediction, the Phillies are coming as -225 home favorites. The Phillies have been struggling since they clinched their playoff spot, while on the other hand, the Marlins still have mathematical chances for a Wild Card spot, and are playing their best baseball of the season in the best possible time. But Cabrera has been unstable for the Marlins lately, with 4+ earned runs in three of his last four starts, and he has been weaker on the road. the Marlins have also been terrible against left-handed pitching, so I like the Philles to win this one comfortably and cover the runline.

Nikos Lagouretos's Pick: Philadelphia Phillies -1.5

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