Minnesota Twins vs Baltimore Orioles Prediction 5/15/25 MLB Picks

The Minnesota Twins and Baltimore Orioles meet Thursday in MLB action at Oriole Park at Camden Yards. Here’s a Minnesota Twins vs Baltimore Orioles Prediction. This article will include a Minnesota Twins vs Baltimore Orioles Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 23-20 on the year and play the Brewers, Guardians, and Royals next. The Minnesota Twins are batting .239 on the season, have a .310 OBP, and a .380 slugging percentage. The Minnesota Twins pitching staff has a 3.38 ERA and a 1.17 WHIP. Byron Buxton leads the Minnesota Twins with 40 hits and 26 RBI, while Ty France and Trevor Larnach have combined for 78 hits and 44 RBI. 

Chris Paddack gets the ball for the Minnesota Twins, and he is 1-3 with a 4.76 ERA and 30 strikeouts this season. Paddack is 2-1 with a 6.19 ERA and 10 strikeouts in his career against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 15-26 on the year and play the Nationals, Brewers, and Red Sox next. The Baltimore Orioles are batting .227 on the season, have a .296 OBP, and a .384 slugging percentage. The Baltimore Orioles pitching staff has a 5.37 ERA and a 1.49 WHIP. Gunnar Henderson leads the Baltimore Orioles with 38 hits and 12 RBI, while Cedric Mullins and Ryan Mountcastle have combined for 64 hits and 39 RBI.

Tomoyuki Sugano gets the ball for the Baltimore Orioles, and he is 4-2 with a 2.72 ERA and 26 strikeouts this season. This will be Sugano’s first career game against the Minnesota Twins.

Why the Baltimore Orioles will win

• The Twins have lost each of their last 12 Thursday day games as road underdogs against American League opponents.
• The Orioles have led after 3 innings in each of their last four day games against AL Central opponents.
• The Twins have trailed after 5 innings in four of their last five day games.

Why the Minnesota Twins will win

• The Orioles have lost each of their last 11 games as home favorites against the Twins following a home loss.
• The Twins have won each of their last 10 games as road underdogs against the Orioles following a win.
• The Orioles have failed to cover the run line in each of their last 12 games as home favorites against the Twins following a loss.
• The Twins have covered the run line in each of their last 10 games as road underdogs against the Orioles following a win.
• The Orioles have lost the first inning in three of their last four games.

Baltimore Orioles Player Prop Facts

• Gunnar Henderson has hit a home run in four of the Orioles’ last five games against the Twins at Oriole Park at Camden Yards.
• Gunnar Henderson has recorded two or more hits in each of the Orioles’ last five home games against the Twins.
• Gunnar Henderson has recorded at least one RBI in each of the Orioles’ last five games as favorites against the Twins.
• Ryan Mountcastle has scored at least one run in each of his last five home appearances against the Twins.
• Gunnar Henderson has recorded at least one Single in each of the Orioles’ last six day games against opponents that held a winning record.

Minnesota Twins Player Prop Facts

• Trevor Larnach has hit a home run in two of the Twins’ last three games against the Orioles.
• Trevor Larnach has recorded at least one RBI in each of the Twins’ last four road games against AL East opponents.
• Byron Buxton has scored a run in each of his eight previous appearances at Oriole Park at Camden Yards against AL opponents that held a losing record.
• Harrison Bader has recorded at least one hit in each of his last nine appearances with his team as an underdog against AL East opponents.
• Christian Vazquez has recorded at least one Single in each of his last five road appearances against AL East opponents.

Minnesota Twins vs Baltimore Orioles Prediction

The Twins have won 10 straight games, and that includes winning a doubleheader yesterday. We were on the Twins in both games, as I’ve said a few times lately, that the Orioles aren’t a good team. The Orioles are better than their record, but at some point, they need to cash tickets. The Orioles look awful right now. Sugano has been great this season with a 2.72 ERA and 1.10 WHIP through 46.1 innings, but I don’t trust the team he pitches for. Paddack has held his own lately, allowing 12 earned runs in his last 36.1 innings. We’re getting plus money to fade the Orioles. Better yet, we’re getting plus money to back a team that hasn’t lost since May 2. Give me the Twins. 

Randy Chambers's Pick: Minnesota Twins +114