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Minnesota Twins vs Kansas City Royals Prediction 9/6/2025 Today’s MLB Picks

Sep 5, 2025; Kansas City, Missouri, USA;  Kansas City Royals third baseman Maikel Garcia (11) throws his bat to the ground after hitting a two-run home run in the third inning against the Minnesota Twins at Kauffman Stadium. Mandatory Credit: Peter Aiken-Imagn Images

Sep 5, 2025; Kansas City, Missouri, USA; Kansas City Royals third baseman Maikel Garcia (11) throws his bat to the ground after hitting a two-run home run in the third inning against the Minnesota Twins at Kauffman Stadium. Mandatory Credit: Peter Aiken-Imagn Images

MATCHUP Twins Minnesota Royals Kansas City
Team Records 62-80 73-69
Where Kauffman Stadium, Kansas City, Missouri
When Saturday, September 6, 2025
Time 07:15 PM EDT
TV FOX
In this article, we will formulate a Twins vs Royals Prediction for this MLB game on Saturday, September 6th at the Kauffman Stadium in the second game of this series, with the Royals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Kansas City Royals Preview

The Kansas City Royals have a 72-69 record this season and are sitting on the second place of the AL Central. The Royals have a 39-34 home record and are 59-81 in over/under. They are coming off a 2-1 home victory over the Twins, and have back-to-back wins. Under is 7-0 in their last 7 games and are playing the Phillies and the Guardians next.

The Royals have a .244 batting average this season, .305 OBP and .393 Slugging percentage. Kansas’ pitching staff has a 3.64 ERA and 1.24 WHIP. Bobby Witt Jr. leads the Royals with 160 hits, while Maikel Garcia is the team’s best hitter with a .294 batting average. Vinnie Pasquantino leads the team in RBI, with 96, and a team-high 29 home runs.

Stephen Kolek (R) is the projected starter for the Royals, and he has a 13-7 record, 3.08 ERA and 0.97 WHIP.

Minnesota Twins Preview

The Minnesota Twins have a 62-79 record this season and are sitting on the 4th place of the AL Central. The Twins have a 27-43 road record and are 66-66 in over/under. They are coming off a 1-2 road defeat by the Royals, and are 1-6 in their last 7 games. Over is 12-3 in their last 15 games and are playing the Angels and the Diamondbacks next.

The Twins have a .239 batting average this season, .312 OBP and .397 Slugging percentage. Minnesota’s pitching staff has a 4.53 ERA and 1.32 WHIP. Trevor Larnach leads the Twins with 116 hits, while Byron Buxton adds team-highs both in RBI, with 72, and in home runs, with 29. He is also the team’s best hitter with a .271 batting average.

Joe Ryan (R) is the projected starter for the Twins, and he has a 4-5 record, 3.99 ERA and 1.26 WHIP.

Why the Kansas City Royals will win

Why the Minnesota Twins will win

Total Runs Facts

Matchup/League Facts

Twins vs Royals Prediction

Both teams are tied 5-5 wins in their last 10 head-to-head meetings, but the Royals are 4-1 in their last 5 meetings in Kansas City. Under is 9-2 in their last 11 meetings.

In this Twins vs Royals Prediction, the Twins are coming as -125 road favorites. The Twins look like they have given up on the season, so taking them as road favorites is out of the question, even with Ryan on the mound, who has 11 earned runs in his last three starts. Kolek had a quality start in his first start with the Royals, and Kansas City has a superior bullpen to back him up. I like the hosts as home dogs in this one, so take the Kansas City Royals and the plus money in this one.

Nikos Lagouretos's Pick: Kansas City Royals +107

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