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Minnesota Twins vs Los Angeles Angels Prediction 9/9/2025 Today’s MLB Picks

Sep 8, 2025; Anaheim, California, USA;  Minnesota Twins third baseman Royce Lewis (23) hits a two-run home run during the fifth inning against the Los Angeles Angels at Angel Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

Sep 8, 2025; Anaheim, California, USA; Minnesota Twins third baseman Royce Lewis (23) hits a two-run home run during the fifth inning against the Los Angeles Angels at Angel Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

MATCHUP Twins Minnesota Angels Los Angeles
Team Records 64-81 68-77
Where Angel Stadium, Anaheim, California
When Tuesday, September 9, 2025
Time 09:38 PM EDT
TV FanDuel SN West

In this article, we will formulate a Twins vs Angels Prediction for this MLB game on Tuesday, September 9th at the Angel Stadium in the second game of this series, with the Twins having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 67-77 record this season and are sitting on the 4th place of the AL West. The Angels have a 35-38 home record and 78-63 in over/under They are coming off a 3-12 home defeat by the Twins, and are 1-4 in their last 5 games. Over is 3-1 in their last 4 games and are playing the Mariners and the Brewers next.

The Angels have a .227 batting average this season, .303 OBP and .399 Slugging percentage. LA’s pitching staff has a 4.84 ERA and 1.44 WHIP. Zach Neto leads the Angels with 126 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 95 RBI, while Jo Adell adds a team-high 35 home runs.

Kyle Hendricks (R) is the projected starting pitcher for the Angels, and he has a 6-9 record, 4.81 ERA and 1.30 WHIP.

Minnesota Twins Preview

The Minnesota Twins have a 64-80 record this season and are sitting on the 4th place of the AL Central. The Twins have a 29-44 road record and are 68-67 in over/under. They are coming off a 12-3 road victory over the Angels, and have back-to-back wins. Over is 8-3 in their last 11 games and are playing the Yankees and the Diamondbacks next.

The Twins have a .239 batting average this season, .312 OBP and .398 Slugging percentage. Minnesota’s pitching staff has a 4.55 ERA and 1.33 WHIP. Trevor Larnach leads the Twins with 117 hits, while Byron Buxton adds team-highs both in RBI, with 74, and in home runs, with 30. He is also the team’s best hitter with a .271 batting average.

Zebby Matthews (R) is the projected starter for the Twins, and he has a 4-4 record, 4.73 ERA and 1.42 WHIP.

Minnesota Twins @ Los Angeles Angels Betting Trends: September 9, 2025

Why the Los Angeles Angels will win

Why the Minnesota Twins will win

Total Runs Facts

Los Angeles Angels Player Prop Facts

Minnesota Twins Player Prop Facts

Matchup/League Facts

Twins vs Angels Prediction

The Twins are 10-1 in their last 11 head-to-head meetings against the Angels, and have won their last 4 visits in Los Angeles. Over is 7-3-1 in their last 11 meetings.

In this Twins vs Angels Prediction, the Twins are coming as -120 road favorites. I don’t trust either pitcher in this matchup, as they both have an ERA close to 5.00. Matthews has been terrible on the road for the Twins, with a 5.77 ERA, while Hendricks is coming into this matchup in poor form for the Angels, with a 5.61 ERA across his last five starts. Hendricks has torched in his previous start against the Twins this season, having given up 7 runs in just 3 innings of work. The opening game of this series had 15 total runs, and I expect another high-scoring affair today. Take the over 9 runs in this one.

Nikos Lagouretos's Pick: Over 9

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