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Oakland Athletics vs Boston Red Sox Prediction 9/16/2025 Today’s MLB Picks

Aug 26, 2025; West Sacramento, California, USA; Athletics left fielder Tyler Soderstrom (21) hits an RBI single during the third inning against the Detroit Tigers at Sutter Health Park. Mandatory Credit: Sergio Estrada-Imagn Images

Aug 26, 2025; West Sacramento, California, USA; Athletics left fielder Tyler Soderstrom (21) hits an RBI single during the third inning against the Detroit Tigers at Sutter Health Park. Mandatory Credit: Sergio Estrada-Imagn Images

MATCHUP Athletics Oakland Red Sox Boston
Team Records 71-80 82-69
Where Fenway Park, Boston, Massachusetts
When Tuesday, September 16, 2025
Time 06:45 PM EDT
TV NESN

The Athletics and the Boston Red Sox meet Tuesday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Athletics vs. Boston Red Sox prediction.

Starting Pitching Matchup

The Athletics will send out Jeffrey Springs for the start here and Springs is 10-11 with a 4.28 ERA and 132 strikeouts this season. In his last five starts against the Red Sox, Springs is 0-3 with a 5.40 ERA and 24 strikeouts. Connelly Early will start this one for the Red Sox and is 1-0 with a 0.00 ERA and 11 strikeouts this season. This will be Early’s second career start against the Athletics.

Athletics Recap

The Athletics come into this game looking to build on their 7-4 win over the Cincinnati Reds last time out to sit at 70-80 this season. After this series, the Athletics will head on the road once again for a series against the Pittsburgh Pirates.

Athletics Win Four In A Row

Jacob Wilson has 142 hits, 23 doubles and a .318 batting average while Tyler Soderstrom has 144 hits with 30 doubles, 24 home runs and 88 RBIs this season. Brent Rooker has 158 hits with 40 doubles, 29 home runs and 85 RBIs but also has 139 strikeouts this season while Nick Kurtz has a team-high 32 home runs and 80 RBIs with 24 doubles. Shea Langeliers has 117 hits with 30 home runs and 68 RBIs while Lawrence Butler’s also chipped in 20 stolen bases and 29 doubles as part of his 127 hits as well as 20 home runs and 59 RBIs while also owning a team-high 169 strikeouts this season.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to build on their 6-4 win over the New York Yankees from Sunday’s series finale to sit at 82-68 this season. After this series, the Red Sox will head on the road for a series against the Tampa Bay Rays.

Red Sox Snap Three-Game Losing Streak

Alex Bregman has 110 hits including 27 doubles along with 17 home runs and 59 RBIs this season. Trevor Story’s added 147 hits with 24 home runs, 91 RBIs and 28 stolen bases while Jarren Duran has 148 hits with 39 doubles, 13 triples, 15 home runs, 80 RBIs and a team-high 23 stolen bases. Roman Anthony’s added 75 hits with 18 doubles, 8 home runs and 32 RBIs while Wilyer Abreu has 22 home runs with 69 RBIs and 6 stolen bases and Ceddanne Rafaela has 16 homers, 29 doubles, 3 triples, 60 RBIs and 19 stolen bases this season.

Athletics @ Boston Red Sox Betting Trends: September 16, 2025

Why the Boston Red Sox will win

Why the Athletics will win

Total Runs Facts

Boston Red Sox Player Prop Facts

Athletics Player Prop Facts

Matchup/League Facts

Athletics vs. Boston Red Sox Prediction

I’m on the Athletics here. I think the A’s are in prime position for some revenge here after Early stifled the A’s in his major league debut, as the Athletics have been a solid team against lefties for the better part of the second half of the season. Springs has been a much better option away from Sutter Health Park this season and I think the Athletics keep the ball rolling with a win here. Give me the A’s.

Chris Ruffolo's Pick: Athletics +115

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