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Philadelphia Phillies vs Arizona Diamondbacks Prediction 9/20/2025 Today’s MLB Picks

Sep 15, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks pitcher Zac Gallen (23) pitches against the San Francisco Giants during the first inning at Chase Field. Mandatory Credit: Joe Camporeale-Imagn Images

Sep 15, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks pitcher Zac Gallen (23) pitches against the San Francisco Giants during the first inning at Chase Field. Mandatory Credit: Joe Camporeale-Imagn Images

MATCHUP Phillies Philadelphia Diamondbacks Arizona
Team Records 92-63 78-77
Where Chase Field, Phoenix, Arizona
When Saturday, September 20, 2025
Time 08:10 PM EDT
TV MLB.TV

The Philadelphia Phillies and the Arizona Diamondbacks meet Saturday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Philadelphia Phillies will send out Aaron Nola here and Nola is 4-9 with a 6.44 ERA and 84 strikeouts this season. In his last five starts against the Phillies, Nola is 2-2 with a 5.67 ERA and 33 strikeouts. Zac Gallen will get the nod for the Diamondbacks here and is 12-14 with a 4.73 ERA and 163 strikeouts this season. In his last five starts against the Phillies, Gallen is 2-1 with a 2.66 ERA and 21 strikeouts.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to build on their 8-2 win over the Diamondbacks in Friday’s series opener to sit at 92-62 this season. After this series, the Phillies will head home for a series against the Miami Marlins.

Phillies Win 8 Of Their Last 10

Nick Castellanos has 134 hits with 27 doubles including 17 home runs and 69 RBIs while Kyle Schwarber has 138 hits with a team-high 53 home runs and 128 RBIs but also has a team-high 183 strikeouts as well on the year. Bryce Harper has 12 stolen bases, 32 doubles, 27 home runs and 75 RBIs. Trea Turner also has 179 hits with 7 triples, 15 home runs, 69 RBIs and a team-high 36 stolen bases. Max Kepler has 18 doubles and Bryson Stott has 20 doubles, 3 triples, 12 homers and 65 RBIs while Stott also has 23 stolen bases as well this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to rebound from their loss at the hands of the Phillies in Friday’s matchup to sit at 77-77 this season. After this series, the Diamondbacks will take ont he Los Angeles Dodgers in a series at home.

Diamondbacks Lose Back-To-Back Games

Corbin Carroll has 140 hits with 30 home runs, 78 RBIs, 17 triples and 30 doubles this season. Carroll also has a team-high 29 stolen bases and Geraldo Perdomo has 26 stolen bases as well as 19 home runs and 97 RBIs with a team-high 163 hits this season. Ketel Marte’s added 26 home runs and 67 RBIs as well on the year and Lourdes Gurriel has 124 hits with 24 doubles, 19 home runs and 80 RBIs.

Philadelphia Phillies @ Arizona Diamondbacks Betting Trends: September 20, 2025

Why the Arizona Diamondbacks will win

Why the Philadelphia Phillies will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Philadelphia Phillies Player Prop Facts

Matchup/League Facts

Philadelphia Phillies vs. Arizona Diamondbacks Prediction

I’m on the Diamondbacks in this one. I know the Phillies looked solid in the opener, and I never thought I’d say this, but Zac Gallen has been the far more reliable and consistent option in his recent starts. Aaron Nola can be ace level, or he can give up six runs in a start like he did last time out, and I think the Diamondbacks, who have been solid against righties all year long, can get to him here. The Diamondbacks are still trying to keep their season alive too, so I’ll take a shot on the Diamondbacks at home in this one.

Chris Ruffolo's Pick: Arizona -111

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