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Pittsburgh Pirates vs Atlanta Braves Prediction 9/26/2025 Today’s MLB Picks

Sep 23, 2025; Cumberland, Georgia, USA; Atlanta Braves right fielder Ronald Acuna Jr (13) reacts after hitting a home run against the Washington Nationals during the sixth inning at Truist Park. Mandatory Credit: Dale Zanine-Imagn Images

Sep 23, 2025; Cumberland, Georgia, USA; Atlanta Braves right fielder Ronald Acuna Jr (13) reacts after hitting a home run against the Washington Nationals during the sixth inning at Truist Park. Mandatory Credit: Dale Zanine-Imagn Images

MATCHUP Pirates Pittsburgh Braves Atlanta
Team Records 70-90 75-85
Where Truist Park, Atlanta, Georgia
Time Sep 26th, 11:15 PM Z
TV MLB.TV

The Pittsburgh Pirates and the Atlanta Braves meet Friday in MLB action from Truist Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Pittsburgh Pirates vs. Atlanta Braves prediction.

Starting Pitching Matchup

The Pittsburgh Pirates will send out Mitch Keller for the start here and Keller is 6-15 with a 4.22 ERA and 144 strikeouts this season. In his last five starts against Atlanta, Keller is 1-3 with a 6.75 ERA and 23 strikeouts. Joey Wentz will get the nod for the Braves here and is 5-6 with a 5.46 ERA and 89 strikeouts this season. This will be Wentz’s first career start against Pittsburgh.

Pittsburgh Pirates Recap

The Pittsburgh Pirates come into this game looking to bounce back from their 2-1 loss at the hands of Cincinnati last time out to fall to 69-90 this season. 

Pirates Have Four-Game Win Streak Snapped

Bryan Reynolds has 140 hits with 37 doubles, 16 home runs and 73 RBIs while also posting 171 strikeouts so far this season. Oneil Cruz has posted a team-high 20 home runs and 61 RBIs with 38 stolen bases. Cruz also has 173 strikeouts as well this season. Tommy Pham has 17 doubles and Andrew McCutchen has 112 hits with 22 doubles as well this season.

Atlanta Braves Recap

The Atlanta Braves come into this game looking to bounce back from their 4-3 loss at the hands of the Washington Nationals last time out to drop to 75-83 this season. 

Braves Have Win Streak Snapped

Austin Riley has 108 hits including 16 home runs, 54 RBIs and 20 doubles so far this season. Ozzie Albies has 145 hits with 23 doubles, 16 home runs and 74 RBIs in addition to 14 stolen bases and Matt Olson has 167 hits with 40 doubles, 28 home runs and 93 RBIs of his own. Marcell Ozuna also has 111 hits with 21 home runs and 67 RBIs. Michael Harris II also has 148 hits with 25 doubles, 6 triples, 19 home runs and 85 RBIs and 20 stolen bases as well and Nick Allen has 8 stolen bases as well this season.

Pittsburgh Pirates @ Atlanta Braves Betting Trends: September 26, 2025

Why the Atlanta Braves will win

Why the Pittsburgh Pirates will win

Total Runs Facts

Atlanta Braves Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Matchup/League Facts

Pittsburgh Pirates vs. Atlanta Braves Prediction

I’m siding with Atlanta in this one. Two teams with nothing to play for but pride and contract incentives/obligations here, but I think the Braves are not only the better team but I think Joey Wentz is the better starting option. Mitch Keller’s had issues this season and the Braves have been hitting righties well as of late while the Pirates have had issues of their own against lefties and issues on the road for much of the season. Give me Atlanta here.

Chris Ruffolo's Pick: Atlanta -155

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