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Pittsburgh Pirates vs Washington Nationals Prediction 9/13/2025 Today’s MLB Picks

Sep 12, 2025; Washington, District of Columbia, USA; Pittsburgh Pirates second base Nick Gonzales (39) slides into second base as a throw by Washington Nationals first base Josh Bell (not pictured) on a ground ball by Pirates outfielder Oneil Cruz (not pictured) sails past Nationals shortstop CJ Abrams (5) during the second inning at Nationals Park. Mandatory Credit: Geoff Burke-Imagn Images

Sep 12, 2025; Washington, District of Columbia, USA; Pittsburgh Pirates second base Nick Gonzales (39) slides into second base as a throw by Washington Nationals first base Josh Bell (not pictured) on a ground ball by Pirates outfielder Oneil Cruz (not pictured) sails past Nationals shortstop CJ Abrams (5) during the second inning at Nationals Park. Mandatory Credit: Geoff Burke-Imagn Images

MATCHUP Pirates Pittsburgh Nationals Washington
Team Records 65-84 61-87
Where Nationals Park, Washington, District of Columbia
When Saturday, September 13, 2025
Time 04:05 PM EDT
TV MASN

In this article, we will formulate a Pirates vs Nationals Prediction for this MLB game on Saturday, September 13th at the Nationals Park the second game of this series, with Nationals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Washington Nationals Preview

The Washington Nationals have a 61-86 record this season and are sitting on the last place of the NL East. The Nationals have a 30-42 home record and are 75-63 in over/under. They are coming off a 6-5 home victory over the Pirates, that ended their two-game losing streak. Over is 7-2 in their last 9 games and are playing the Mets and the Braves next.

The Nationals have a .245 batting average this season, .308 OBP and .391 Slugging percentage. Washington’s pitching staff has a 5.30 ERA and 1.43 WHIP. James Wood leads the Nationals with 143 hits, while CJ Abrams is the team’s best hitter with a .266 batting average. James Wood adds a team-high 88 RBI and leads the team in home runs, with 27.

Andrew Alvarez (L) is the projected starting pitcher for the Nationals, and he has a 1-0 record, 1.86 ERA and 0.93 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 64-84 record this season and are sitting on the last place of the NL Central. They have a 22-51 road record, and are 60-83 in over/under. They are coming off a 2-3 road defeat by the Orioles, and have six consecutive losses. Under is 5-1 in their last 6 games are playing the Cubs and the Athletics next.

The Pirates have a .232 batting average this season, .305 OBP and .350 slugging percentage. Pittsburgh’s pitching staff has a 3.89 ERA and 1.23 WHIP. Bryan Reynolds leads the Pirates with 131 hits, and a team-high 71 RBI. He is also the team’s best hitter with a .242 batting average, while Oneil Cruz leads the team in home runs, with 19.

Reliever Bubba Chandler (R) is the projected starting pitcher for the Pirates, and he has a 2-1 record, 7.36 ERA and 1.50 WHIP.

Pittsburgh Pirates @ Washington Nationals Betting Trends: September 13, 2025

Why the Washington Nationals will win

Why the Pittsburgh Pirates will win

Total Runs Facts

Washington Nationals Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Matchup/League Facts

Pirates vs Nationals Prediction

The Pirates are 4-2 in their last 6 meetings against the Nationals, and under is 3-1 in their last 4 meetings. 

In this Pirates vs Nationals Prediction, the Nationals are coming as -125 home favorites. We know very little for both starting pitchers, but Alvarez for the Nationals has only two earned runs in his two starts this season, while on the flip side, Chandler was torched in his only start this season, having given up 9 runs in 2.2 innings pitched. The Nats have a better offense, and are better against righties, while the Pirates are weaker against lefties, so I like the value with the home team in this one. Take the Washington Nationals on the moneyline at home.

Nikos Lagouretos's Pick: Washington Nationals ML

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