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San Diego Padres vs Seattle Mariners Prediction 8/27/2025 Today’s MLB Picks

Aug 26, 2025; Seattle, Washington, USA; San Diego Padres catcher Freddy Fermin (54) hits an RBI-sacrifice bunt against the Seattle Mariners during the sixth inning at T-Mobile Park. Mandatory Credit: Joe Nicholson-Imagn Images

Aug 26, 2025; Seattle, Washington, USA; San Diego Padres catcher Freddy Fermin (54) hits an RBI-sacrifice bunt against the Seattle Mariners during the sixth inning at T-Mobile Park. Mandatory Credit: Joe Nicholson-Imagn Images

MATCHUP San Diego Padres Seattle Mariners
Team Records 75-58 71-62
Where T-Mobile Park, Seattle, Washington
When Wednesday, August 27, 2025
Time 04:10 PM EDT
TV Root Sports NW

In this article, we will formulate a Padres vs Mariners Prediction for this MLB game on Wednesday, August 27th at the T-Mobile Park in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 71-62 record this season and are sitting on the second place of the AL West. The Mariners have a 40-27 home record and are 72-55 in over/under. They are coming off a 6-7 home defeat by the Mariners, which ended their two-game winning streak. Over is 7-2 in their last 9 games and they are playing the Rays and the Guardians next.

The Mariners have a .242 batting average this season, .318 OBP and .411 Slugging percentage. Seattle’s pitching staff has a 3.98 ERA and 1.26 WHIP. Julio Rodriguez leads the Mariners in hits with 142, while JP Crawford is the team’s best hitter with a .264 batting average. Cal Raleigh leads the team both in RBI with 107, and in home runs with 50.

Bryan Woo (R) is the projected starting pitcher for the Mariners, and he has a 11-7 record, 2.97 ERA and 0.94 WHIP.

San Diego Padres Preview

The San Diego Padres have a 75-58 record this season and are sitting on the second place of the NL West. They have a 32-36 road record, and are 56-73 in over/under. The Padres are coming off a 7-6 road victory over the Mariners, which ended their two-game losing streak. Over is 3-0 in their last 3 games and are playing the Twins and the Orioles next. 

The Padres have a .252 batting average this season, .322 OBP and .386 Slugging percentage. San Diego’s pitching staff has a 3.59 ERA and 1.19 WHIP. Manny Machado leads the Padres with 149 hits and is the team’s best hitter with a .290 batting average. He also leads the team in RBI, with 78, and in home runs, with 21. 

Yu Darvish (R) is the projected starting pitcher for the Padres, and he has a 3-3 record, 5.36 ERA and 1.10 WHIP.

Why the Seattle Mariners will win

Why the San Diego Padres will win

Total Runs Facts

Matchup/League Facts

Padres vs Mariners Prediction

The Mariners are 9-2 in their last 11 head-to-head meetings against the Padres, and are 4-2 their last 4 meetings in Seattle.

In this Padres vs Mariners Prediction, the Mariners are coming as -135 home favorites. The Mariners have the pitching advantage, as Woo takes the mound and he has been elite this season, and even stronger at home, with a 2.28 home ERA. He is back into form, with back-to-back quality starts, while on the other hand, Darvish has not been himself this season for the Padres, and he has been struggling on the road, with a 7.66 road ERA across five road starts. I like this bounce-back spot for the home team, so give me the Mariners on the moneyline at home in a decent price.

Nikos Lagouretos's Pick: Seattle Mariners -138

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