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San Francisco Giants vs Colorado Rockies Prediction 9/3/2025 Today’s MLB Picks

Aug 20, 2025; San Diego, California, USA; San Francisco Giants center fielder Jung Hoo Lee (51) walks back to the dugout after striking out during the seventh inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

Aug 20, 2025; San Diego, California, USA; San Francisco Giants center fielder Jung Hoo Lee (51) walks back to the dugout after striking out during the seventh inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP San Francisco Giants Colorado Rockies
Team Records 70-69 39-100
Where Coors Field, Denver, Colorado
When Wednesday, September 3, 2025
Time 08:40 PM EDT
TV NBC Sports BA

The San Francisco Giants and the Colorado Rockies meet Wednesday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Colorado Rockies Prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Robbie Ray here and Ray is 10-6 with a 3.18 ERA and 163 strikeouts this season. In his last five starts against the Rockies, Ray is 1-1 with a 4.79 ERA and 29 strikeouts. German Marquez will get the nod for the Rockies here and Marquez is 3-12 with a 6.14 ERA and 73 strikeouts this season. In his last five starts against the Giants, Marquez is 1-4 with a 7.11 ERA and 28 strikeouts.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to build on their 7-4 win over the Rockies from Tuesday’s matchup to improve to 70-69 this season. After this series, the Giants will take to the road for a series against the St. Louis Cardinals.

Giants Win 9 Of Last 10 Games

Jung Hoo Lee has 126 hits including a team-high 30 doubles along with 10 triples, 7 home runs and 48 RBIs with 10 stolen bases while Heliot Ramos has 139 hits with 23 doubles, 16 home runs and 58 RBIs. Wilmer Flores also 14 home runs and 64 RBIs while Tyler Fitzgerald has 9 stolen bases as well on the year. Matt Chapman also has 86 hits with 18 home runs and 50 RBIs along with 16 doubles and Willy Adames has 115 hits with 18 doubles, 25 home runs and 72 RBIs of his own this season. 

Why the San Francisco Giants will win

San Francisco Giants Player Prop Facts

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their loss at the hands of the Giants on Tuesday to drop to 39-100 this season. After this series, the Rockies will square off against another division rival at home in the San Diego Padres.

Rockies Drop 8 Of Last 10

Hunter Goodman leads the Rockies with 123 hits including 23 doubles, 4 triples, 26 home runs and 76 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 126 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 14 home runs, 23 doubles, 44 RBIs, 5 triples and 14 stolen bases. Brenton Doyle has 103 hits with 19 doubles, 14 home runs, 53 RBIs and 15 stolen bases. Mickey Moniak has 94 hits with 17 doubles, 8 triples and 18 home runs with 55 RBIs. 

Why the Colorado Rockies will win

Colorado Rockies Player Prop Facts

Total Runs Facts

San Francisco Giants vs. Colorado Rockies Prediction

I’m on the over here. The Rockies have been more competitive at times than we’re used to them being, especially competitive for a 100-win team, while the Giants should be able to get to Marquez, and they have scored 15 runs in the first two games of this series. Robbie Ray hasn’t had a ton of luck at Coors either, so I’m banking on runs in this game. Give me the over.

Chris Ruffolo's Pick: Over 11

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