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San Francisco Giants vs Los Angeles Dodgers Prediction 9/19/2025 Today’s MLB Picks

Sep 18, 2025; Los Angeles, California, USA;  San Francisco Giants shortstop Willy Adames (2) reacts after strike out looking during the seventh inning against the Los Angeles Dodgers at Dodger Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

Sep 18, 2025; Los Angeles, California, USA; San Francisco Giants shortstop Willy Adames (2) reacts after strike out looking during the seventh inning against the Los Angeles Dodgers at Dodger Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

MATCHUP Giants San Francisco Dodgers Los Angeles
Team Records 76-78 87-67
Where Dodger Stadium, Los Angeles, California
When Friday, September 19, 2025
Time 10:10 PM EDT
TV Apple TV+

The San Francisco Giants and Los Angeles Dodgers meet Friday in MLB action at Dodger Stadium. Here’s a San Francisco Giants vs Los Angeles Dodgers Prediction. This article will include a San Francisco Giants vs Los Angeles Dodgers Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 76-77 on the year and play the Cardinals and Rockies next. The San Francisco Giants are batting .235 on the season, have a .311 OBP, and a .385 slugging percentage. The San Francisco Giants pitching staff has a 3.83 ERA and a 1.30 WHIP. Heliot Ramos leads the San Francisco Giants with 149 hits and 61 RBI, while Jung Hoo Lee and Willy Adames have combined for 265 hits and 134 RBI.

Robbie Ray gets the ball for the San Francisco Giants, and he is 11-7 with a 3.50 ERA and 181 strikeouts this season. Ray is 9-7 with a 3.54 ERA and 184 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 86-67 on the year and play the Diamondbacks and Mariners next. The Los Angeles Dodgers are batting .254 on the season, have a .329 OBP, and a .439 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.03 ERA and a 1.27 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 164 hits and 95 RBI while Freddie Freeman and Andy Pages have combined for 307 hits and 165 RBI.

Clayton Kershaw gets the ball for the Los Angeles Dodgers, and he is 10-2 with a 3.53 ERA and 71 strikeouts this season. Kershaw is 27-16 with a 2.08 ERA and 415 strikeouts in his career against the San Francisco Giants.

San Francisco Giants @ Los Angeles Dodgers Betting Trends: September 19, 2025

Why the Los Angeles Dodgers will win

Why the San Francisco Giants will win

Total Runs Facts

Los Angeles Dodgers Player Prop Facts

San Francisco Giants Player Prop Facts

Matchup/League Facts

San Francisco Giants vs Los Angeles Dodgers Prediction

The Giants are worth a look with Ray on the mound, as he’s been a top-25 pitcher this season and has a 3.28 ERA and .203 allowed batting average on the road. However, the Giants have fallen off a cliff over the last two weeks and are on the outside looking in regarding the wild card race. Ray has also allowed 22 hits and 17 earned runs in his last 18 innings, which includes just getting tagged by these Dodgers. Kershaw is having a shaky September, but he’s been solid overall, and the Dodgers have won 7 of his last 8 starts. There should also be an electric atmosphere after Kershaw said he’s retiring after the season. Expect some extra juice. Give me the Dodgers.

Randy Chambers's Pick: Los Angeles Dodgers

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