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Seattle Mariners vs Kansas City Royals Prediction 9/17/2025 Today’s MLB Picks

Sep 16, 2025; Kansas City, Missouri, USA; Seattle Mariners pinch running Leo Rivas (76) slides safely into second base as Kansas City Royals second baseman Jonathan India (6) fields the ball during the eighth inning at Kauffman Stadium. Mandatory Credit: Scott Sewell-Imagn Images

Sep 16, 2025; Kansas City, Missouri, USA; Seattle Mariners pinch running Leo Rivas (76) slides safely into second base as Kansas City Royals second baseman Jonathan India (6) fields the ball during the eighth inning at Kauffman Stadium. Mandatory Credit: Scott Sewell-Imagn Images

MATCHUP Mariners Seattle Royals Kansas City
Team Records 83-69 76-76
Where Kauffman Stadium, Kansas City, Missouri
When Wednesday, September 17, 2025
Time 07:40 PM EDT
TV MLB.TV

The Seattle Mariners and Kansas City Royals meet Wednesday in MLB action at Kauffman Stadium. Here’s a Seattle Mariners vs Kansas City Royals Prediction. This article will include a Seattle Mariners vs Kansas City Royals Pick.

Seattle Mariners Betting Preview

The Seattle Mariners are 83-68 on the year and play the Astros, Rockies, and Dodgers next. The Seattle Mariners are batting .244 on the season, have a .321 OBP, and a .419 slugging percentage. The Seattle Mariners pitching staff has a 3.92 ERA and a 1.24 WHIP. Julio Rodriguez leads the Seattle Mariners with 167 hits and 93 RBI, while J.P. Crawford and Randy Arozarena have combined for 279 hits and 125 RBI.

Bryce Miller gets the ball for the Seattle Mariners, and he is 4-5 with a 5.59 ERA and 64 strikeouts this season. Miller is 0-0 with a 10.00 ERA and 7 strikeouts in his career against the Kansas City Royals.

Kansas City Royals Betting Preview

The Kansas City Royals are 75-76 on the year and play the Blue Jays, Angels, and Athletics next. The Kansas City Royals are batting .244 on the season, have a .305 OBP, and a .391 slugging percentage. The Kansas City Royals pitching staff has a 3.78 ERA and a 1.26 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 167 hits and 79 RBI while Maikel Garcia and Vinnie Pasquantino have combined for 311 hits and 174 RBI.

Cole Ragans gets the ball for the Kansas City Royals, and he is 2-3 with a 5.18 ERA and 76 strikeouts this season. Ragans is 0-0 with a 1.29 ERA and 11 strikeouts in his career against the Seattle Mariners.

Seattle Mariners @ Kansas City Royals Betting Trends: September 17, 2025

Why the Kansas City Royals will win

Why the Seattle Mariners will win

Total Runs Facts

Kansas City Royals Player Prop Facts

Seattle Mariners Player Prop Facts

Seattle Mariners vs Kansas City Royals Prediction

The Royals pitching staff continues to get rocked, and now they’re throwing out Ragans who has an ERA over 5 and a 1.29 WHIP. Ragans also hasn’t pitched since June as he’s been dealing with a shoulder injury. Miller has had issues himself this season, but the Mariners have won 10 straight games and make a push for the AL West crown. We’ve been blindly backing the M’s during this stretch, and there’s no reason to turn back now. Give me the Mariners to keep things rolling.

Randy Chambers's Pick: Seattle Mariners

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