| MATCHUP | Cardinals St. Louis | Brewers Milwaukee |
|---|---|---|
| Team Records | 72-77 | 91-58 |
| Where | American Family Field, Milwaukee, Wisconsin | |
| When | Saturday, September 13, 2025 | |
| Time | 08:15 PM EDT | |
| TV | FOX | |
In this article, we will formulate a Cardinals vs Brewers Prediction for this MLB game on Saturday, September 13th at the American Family Field the second game of this series, with the Brewers having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.
Milwaukee Brewers Preview
The Milwaukee Brewers have a 90-58 record this season and are sitting on the first place of the NL Central. They have a 47-26 home record and are 71-72 in over/under. They are coming off an 8-2 home victory over the Cardinals, which ended their three-game losing streak. Over is 4-1 in their last 5 games and are playing the Cardinals and the Angels next.
The Brewers have a .260 batting average this season, .333 OBP and .408 Slugging percentage. Milwaukee’s pitching staff has a 3.62 ERA and 1.23 WHIP. Brice Turang leads the Brewers with 155 hits, while Christian Yelich leads the team in RBI, with 95, adding a team-high 28 home runs. Sal Frelick is the team’s best hitter with a .294 batting average.
Jacob Misiorowski (R) is the projected starting pitcher for the Brewers, and he has a 5-2 record, 4.09 ERA and 1.09 WHIP.
Saint Louis Cardinals Preview
The Saint Louis Cardinals have a 72-76 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 31-42 road record and are 74-66 in over/under. They are coming off a 2-8 road defeat by the Mariners, and have three straight losses. Under is 5-3 in their last 8 games and are playing the Brewers and the Reds next.
The Cardinals have a .245 batting average this season, .313 OBP and .378 Slugging percentage. Saint Louis’ pitching staff has a 4.27 ERA and 1.32 WHIP. Alec Burleson leads the Cardinals with 127 hits, and he is the team’s best hitter with a .283 batting average. Wilson Contreras leads the team in RBI, with 78, adding a team-high 20 home runs.
Sonny Gray (R) is the projected starting pitcher for the Cardinals, and he has a 13-8 record, 4.45 ERA and 1.22 WHIP.
St. Louis Cardinals @ Milwaukee Brewers Betting Trends: September 13, 2025
- Probable Starting Pitcher: Jacob Misiorowski Record this season: 5-2 ERA: 4.09
- Home Record: 3-0
- Last 5 against Cardinals: 1-0
Why the Milwaukee Brewers will win
- The Brewers have won each of their last nine games against NL Central opponents that held a losing record.
- The Cardinals have lost each of their last five road games.
- The Brewers have covered the run line each of their last nine games against NL Central opponents that held a losing record.
- The Cardinals have failed to cover the run line in each of their last six games following a road loss.
- The Brewers have led after 5 innings in each of their last six home games against NL Central opponents that held a losing record.
- The Cardinals have lost the first inning in three of their last four road games against NL Central opponents that held a winning record.
- The Brewers have led after 3 innings in each of their last six home games against NL Central opponents that held a losing record.
- Probable Starting Pitcher: Sonny Gray Record this season: 13-8 ERA: 4.45
- Road Record: 4-3
- Last 5 against Brewers: 0-3
Why the St. Louis Cardinals will win
- The Brewers have lost each of their last four games as home favorites after playing the previous day.
- The Cardinals have won each of their last six Saturday games as road underdogs.
- The Brewers have failed to cover the run line in eight of their last nine home games after playing the previous day.
- The Cardinals have covered the run line in each of their last six Saturday games as road underdogs.
- The Brewers have trailed after 5 innings in three of their last four games.
Total Runs Facts
- Six of the Brewers’ last seven home games against NL Central opponents have gone OVER the total runs line.
- Six of the Cardinals’ last seven road games against NL Central opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last seven Saturday night games.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Cardinals’ last seven games as underdogs.
Milwaukee Brewers Player Prop Facts
- Christian Yelich has hit a home run in four of his last five appearances in night games against NL Central teams that held a losing record.
- Christian Yelich has recorded at least one hit in each of his last 19 appearances against NL Central opponents that held a losing record.
- Sal Frelick ranks 9th amongst qualified players for Batting Average (.294) this season.
St. Louis Cardinals Player Prop Facts
- Brendan Donovan has recorded a Double in three of his last four appearances against the Brewers after playing the previous day.
- Willson Contreras has hit a home run in four of his last seven road appearances after playing the previous day.
- Sonny Gray has recorded a win in three of his last four appearances against NL opponents that held a winning record.
- Sonny Gray has recorded six or more strikeouts in 12 of his last 13 appearances with his team as an underdog against NL Central opponents.
- Brendan Donovan has recorded at least one hit in each of his last eight appearances against the Brewers.
- Sonny Gray ranks T8th in the league for Wins (13) this season.
Matchup/League Facts
- The Brewers rank 2nd in the league for runs scored this season (751).
- The Brewers rank 2nd in the league for on-base percentage this season (.333).
- The Cardinals rank T29th in the league for triples this season (8).
- The Cardinals rank 29th in the league for strikeouts this season (1088).
Cardinals vs Brewers Prediction
The Brewers are 5-1 in their last 6 meetings against the Cardinals, and are 4-1 in their last 5 meetings in Milwaukee. Under is 6-3 in their last 9 meetings.
In this Cardinals vs Brewers Prediction, the Brewers are coming as -165 home favorites. Both pitchers have been struggling lately, but Gray has been terrible on the road, with a 5.24 road ERA, and he was torched in his previous start against the Brewers, having given up 6 runs in 4.1 innings pitched. On the flip side, Misiorowski bounced back after a series of bad starts, and he has been excellent at home with a 3-0 record and 2.76 ERA. His previous starts against the Cardinals was a shutout, so I like the Brewers to get the job done once again at home in this one.