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Tampa Bay Rays vs Chicago Cubs Prediction 9/14/2025 Today’s MLB Picks

Sep 13, 2025; Chicago, Illinois, USA; Fans hold up signs for former Chicago Cubs player Anthony Rizzo during a game against the Tampa Bay Rays at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

Sep 13, 2025; Chicago, Illinois, USA; Fans hold up signs for former Chicago Cubs player Anthony Rizzo during a game against the Tampa Bay Rays at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

MATCHUP Rays Tampa Bay Cubs Chicago
Team Records 73-76 85-64
Where Wrigley Field, Chicago, Illinois
When Sunday, September 14, 2025
Time 02:20 PM EDT
TV FanDuel SN Sun

The Tampa Bay Rays and Chicago Cubs meet Sunday in MLB action at Wrigley Field. Here’s a Tampa Bay Rays vs Chicago Cubs Prediction. This article will include a Tampa Bay Rays vs Chicago Cubs Pick.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 73-75 on the year and play the Blue Jays, Red Sox, and Orioles next. The Tampa Bay Rays are batting .252 on the season, have a .313 OBP, and a .404 slugging percentage. The Tampa Bay Rays pitching staff has a 3.90 ERA and a 1.21 WHIP. Yandy Diaz leads the Tampa Bay Rays with 159 hits and 78 RBI, while Junior Caminero and Brandon Lowe have combined for 267 hits and 182 RBI.

Adrian Houser gets the ball for the Tampa Bay Rays, and he is 8-4 with a 3.11 ERA and 83 strikeouts this season. Houser is 4-2 with a 3.98 ERA and 52 strikeouts in his career against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 84-64 on the year and play the Pirates, Reds, and Mets next. The Chicago Cubs are batting .248 on the season, have a .320 OBP, and a .426 slugging percentage. The Chicago Cubs pitching staff has a 3.87 ERA and a 1.19 WHIP. Nico Hoerner leads the Chicago Cubs with 160 hits and 56 RBI while Pete Crow-Armstrong and Dansby Swanson have combined for 267 hits and 161 RBI.

Shota Imanaga gets the ball for the Chicago Cubs, and he is 9-7 with a 3.21 ERA and 101 strikeouts this season. This will be Imanaga’s first career game against the Tampa Bay Rays.

Tampa Bay Rays @ the Chicago Cubs Betting Trends: September 14, 2025

Why the Chicago Cubs will win

Why the Tampa Bay Rays will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Tampa Bay Rays Player Prop Facts

Tampa Bay Rays vs Chicago Cubs Prediction

Houser has been solid this season and the Rays have won his last 5 starts. I still don’t like how the Rays are playing this week overall. Imanaga remains one of the better pitchers in the NL and has allowed 3 or fewer earned runs in 8 straight starts. In 60.2 home innings, Imanaga has a 3.12 ERA and .189 allowed batting average. Quick turnaround, give me the Cubs at home with their ace on the bump.

Randy Chambers's Pick: Chicago Cubs

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