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Tampa Bay Rays vs Chicago White Sox Prediction 9/10/2025 Today’s MLB Picks

Sep 9, 2025; Chicago, Illinois, USA;  Tampa Bay Rays third baseman Junior Caminero (13) doubles during the second inning against the Chicago White Sox at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Sep 9, 2025; Chicago, Illinois, USA; Tampa Bay Rays third baseman Junior Caminero (13) doubles during the second inning against the Chicago White Sox at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Rays Tampa Bay White Sox Chicago
Team Records 72-73 56-90
Where Rate Field, Chicago, Illinois
When Wednesday, September 10, 2025
Time 07:40 PM EDT
TV CHSN

In this article, we will formulate a Rays vs White Sox Prediction for this MLB game on Wednesday, September 10th at the Rate Field in the second game of this series, with the Rays having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 55-90 record this season and are sitting on the last place of the AL Central. The White Sox have a 30-43 home record and are 69-68 in over/under. They are coming off a 4-5 home defeat by the Rays, but are still 7-2 in their last 9 games. Over is 6-2 in their last 8 games and are playing the Guardians and the Orioles next.

The White Sox have a .235 batting average this season, .304 OBP and .378 Slugging percentage. Chicago’s pitching staff has a 4.24 ERA and 1.36 WHIP. Lenyn Sosa leads the White Sox with 123 hits, and he is the team’s best hitter with a .265 batting average. He also leads the team in RBI with 65, adding a team-high 20 home runs.

The White Sox have not yet announced a starting pitcher for this game.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 72-72 record this season and are sitting on the 4th place of the AL East. The Rays have a 34-36 road record and are 62-73 in over/under. They are coming off a 5-4 road victory over the White Sox, that ended their three-game losing streak. Over is 6-3 in their last 9 games and are playing the Cubs and the Blue Jays next.

The Rays have a .252 batting average this season, .313 OBP and .403 slugging percentage. Tampa’s pitching staff has a 3.85 ERA and 1.20 WHIP.  Yandy Diaz leads the Rays with 155 hits, and he is the team’s best hitter with .290 batting average. Junior Caminero leads the team in RBI, with 103 and in home runs, with 41.

Griffin Jax (R) is the projected starting pitcher for the Rays, and he has a 1-7 record, 4.81 ERA and 1.38 WHIP.

Tampa Bay Rays @ the Chicago White Sox Betting Trends: September 10, 2025

Why the Chicago White Sox will win

Why the Tampa Bay Rays will win

Total Runs Facts

Chicago White Sox Player Prop Facts

Tampa Bay Rays Player Prop Facts

Matchup/League Facts

Rays vs White Sox Prediction

The White Sox are 6-4 in their last 10 meetings against the Rays, and are 3-1 in their last 4 meetings in Chicago. Over is 3-1 in their last 4 meetings.

The White Sox were one of the hottest teams in baseball prior to yesterday’s loss, and without a starting pitcher announced, I don’t know what to expect from them. The Rays are going for a bullpen game, and were terrible before yesterday’s win, having scored just 4 total runs in their three games before that. Too many uncertainties in this game, and I will personally stay off this one, but as a slight lean, I would side with the White Sox and possibly the plus money at home.

Nikos Lagouretos's Pick: Chicago White Sox ML

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