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Tampa Bay Rays vs Chicago White Sox Prediction 9/11/2025 Today’s MLB Picks

Sep 10, 2025; Chicago, Illinois, USA; Tampa Bay Rays outfielder Josh Lowe (15) looks on after striking out swinging against the Chicago White Sox during the eighth inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Sep 10, 2025; Chicago, Illinois, USA; Tampa Bay Rays outfielder Josh Lowe (15) looks on after striking out swinging against the Chicago White Sox during the eighth inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Rays Tampa Bay White Sox Chicago
Team Records 72-74 57-90
Where Rate Field, Chicago, Illinois
When Thursday, September 11, 2025
Time 02:10 PM EDT
TV CHSN

The Tampa Bay Rays and Chicago White Sox meet Thursday in MLB action at Rate Field. Here’s a Tampa Bay Rays vs Chicago White Sox Prediction. This article will include a Tampa Bay Rays vs Chicago White Sox Pick.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 72-73 on the year and play the Cubs, Blue Jays, and Red Sox next. The Tampa Bay Rays are batting .252 on the season, have a .314 OBP, and a .405 slugging percentage. The Tampa Bay Rays pitching staff has a 3.87 ERA and a 1.21 WHIP. Yandy Diaz leads the Tampa Bay Rays with 157 hits and 78 RBI, while Junior Caminero and Brandon Lowe have combined for 263 hits and 179 RBI.

Ian Seymour gets the ball for the Tampa Bay Rays, and he is 3-1 with a 2.89 ERA and 47 strikeouts this season. This will be Seymour’s second career game against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 56-90 on the year and play the Guardians, Orioles, and Padres next. The Chicago White Sox are batting .236 on the season, have a .305 OBP, and a .379 slugging percentage. The Chicago White Sox pitching staff has a 4.25 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 124 hits and 67 RBI while Miguel Vargas and Chase Meidroth have combined for 208 hits and 74 RBI.

Shane Smith gets the ball for the Chicago White Sox, and he is 5-7 with a 3.95 ERA and 118 strikeouts this season. This will be Smith’s first career game against the Tampa Bay Rays.

Tampa Bay Rays @ the Chicago White Sox Betting Trends: September 11, 2025

Why the Chicago White Sox will win

Why the Tampa Bay Rays will win

Total Runs Facts

Chicago White Sox Player Prop Facts

Tampa Bay Rays Player Prop Facts

Matchup/League Facts

Tampa Bay Rays vs Chicago White Sox Prediction

Seymour has been strong with his 2.89 ERA and 1.10 WHIP this season, and he has a 1.82 ERA and .148 allowed batting average in 24.2 road innings. The Rays should be favored. However, the Rays are having a rough week, and it’s hard to find confidence to come back to them. The White Sox keep cashing tickets over the last two weeks and as long as it continues, you keep taking shots in the dark. Smith is an all-star, and he has a 3.26 ERA and .183 allowed batting average in 60.2 home innings. I’ll keep backing the White Sox lately. What’s gotten into me?

Randy Chambers's Pick: Chicago White Sox

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