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Texas Rangers vs Houston Astros Prediction 9/17/2025 Today’s MLB Picks

Sep 16, 2025; Houston, Texas, USA; Texas Rangers pinch hitter Adolis Garcia hits an RBI single during the eighth inning against the Houston Astros at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

Sep 16, 2025; Houston, Texas, USA; Texas Rangers pinch hitter Adolis Garcia hits an RBI single during the eighth inning against the Houston Astros at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

MATCHUP Rangers Texas Astros Houston
Team Records 79-74 84-69
Where Daikin Park, Houston, Texas
When Wednesday, September 17, 2025
Time 08:10 PM EDT
TV MLB.TV

In this article, we will formulate a Rangers vs Astros Prediction for this MLB game on Wednesday, September 17th at the Daikin Park in the third game of this series, with the Astros having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros have an 83-69 record this season and are sitting on the second place of the AL West. The Astros have a 45-32 home record and 70-76 in over/under. They are coming off a 6-5 home victory over the Rangers, and are 4-1 in their last 5 games. Over is 4-1 in their last 5 games and are playing the Athletics and the Mariners next.

The Astros have a .253 batting average this season, .318 OBP and .400 slugging percentage. Houston’s pitching staff has a 3.85 ERA and 1.22 WHIP. Jose Altuve leads the Astros with 147 hits, adding a team-high 25 home runs. Jeremy Pena is the team’s best hitter with a .304 batting average, while Christian Walker leads the team in RBI with 82. 

Cristian Javier (R) is the projected starting pitcher for the Astros, and he has a 1-3 record, 4.78 ERA and 1.29 WHIP.

Texas Rangers Preview

The Texas Rangers have a 79-73 record this season and are sitting on the third place of the AL West. The Rangers have a 32-45 road record and are 68-81 in over/under. They are coming off a 5-6 road defeat by the Astros, and have three straight losses. Over is 5-1 in their last 6 games and are playing the Twins and the Marlins next.

The Rangers have a .238 batting average this season, .307 OBP and .388 slugging percentage. Texas’ pitching staff has a 3.44 ERA and 1.17 WHIP.  Josh Smith leads the Rangers with 123 hits, and he is the team’s best hitter with a .257 batting average. Adolis Garcia leads the team in RBI, with 74, while Corey Seager adds a team-high 21 home runs.

Jacob deGrom (R) is the projected starting pitcher for the Rangers, and he has a 12-7 record, 2.82 ERA and 0.92 WHIP.

Texas Rangers @ Houston Astros Betting Trends: September 17, 2025

Why the Houston Astros will win

Why the Texas Rangers will win

Total Runs Facts

Houston Astros Player Prop Facts

Texas Rangers Player Prop Facts

Matchup/League Facts

Rangers vs Astros Prediction

The Astros are 3-1 in their last 4 head-to-head meetings against the Rangers, and are 3-1 their last 4 meetings in Houston. Over is 3-1 in their last 4 meetings.

In this Rangers vs Astros Prediction, the Rangers are coming as -130 road favorites. The Astros have won both games of this series, but the Rangers are putting DeGrom on the mound, who has been elite this season. On the flip side, Javier takes the mound for the Astros, and he has struggled in his last two starts, having 4 earned runs in each one. Texas has the 5th-best bullpen ERA in baseball, and have a slightly better offense than Houston, so I like them in a bounce-back spot today. Take the Texas Rangers on the moneyline on the road.

Nikos Lagouretos's Pick: Texas Rangers -130

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