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Washington Nationals vs Chicago Cubs Prediction 9/7/2025 Today’s MLB Picks

Sep 6, 2025; Chicago, Illinois, USA; Washington Nationals left fielder Daylen Lile (51) celebrates with teammates in the dugout after hitting a solo home run against the Chicago Cubs during the fourth inning at Wrigley Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images

Sep 6, 2025; Chicago, Illinois, USA; Washington Nationals left fielder Daylen Lile (51) celebrates with teammates in the dugout after hitting a solo home run against the Chicago Cubs during the fourth inning at Wrigley Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images

MATCHUP Nationals Washington Cubs Chicago
Team Records 58-84 81-62
Where Wrigley Field, Chicago, Illinois
When Sunday, September 7, 2025
Time 02:20 PM EDT
TV Marquee Sports Net

The Washington Nationals and Chicago Cubs meet Sunday in MLB action at Wrigley Field. Here’s a Washington Nationals vs Chicago Cubs Prediction. This article will include a Washington Nationals vs Chicago Cubs Pick.

Washington Nationals Betting Preview

The Washington Nationals are 57-84 on the year and play the Marlins, Pirates, and Braves next. The Washington Nationals are batting .243 on the season, have a .307 OBP, and a .386 slugging percentage. The Washington Nationals pitching staff has a 5.30 ERA and a 1.43 WHIP. James Wood leads the Washington Nationals with 35 hits and 86 RBI, while CJ Abrams and Luis Garcia Jr. have combined for 245 hits and 113 RBI.

Andrew Alvarez gets the ball for the Washington Nationals, and he is 1-0 with a 0.00 ERA and 4 strikeouts this season. This will be Alvarez’s first career game against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 81-61 on the year and play the Braves, Rays, and Pirates next. The Chicago Cubs are batting .249 on the season, have a .320 OBP, and a .428 slugging percentage. The Chicago Cubs pitching staff has a 3.87 ERA and a 1.20 WHIP. Nico Hoerner leads the Chicago Cubs with 149 hits and 56 RBI while Pete Crow-Armstrong and Kyle Tucker have combined for 265 hits and 128 RBI.

Drew Pomeranz gets the ball for the Chicago Cubs, and he is 2-1 with a 2.45 ERA and 42 strikeouts this season. Pomeranz is 2-1 with a 3.00 ERA and 24 strikeouts in his career against the Washington Nationals.

Washington Nationals @ the Chicago Cubs Betting Trends: September 7, 2025

Why the Chicago Cubs will win

Why the Washington Nationals will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Washington Nationals Player Prop Facts

Matchup/League Facts

Washington Nationals vs Chicago Cubs Prediction

Alvarez looked great in his MLB opener, holding the Marlins to 1 hit and 0 runs in 5 frames. However, it was just one game and it was at home. The jury is still out. We’ll learn more about Alvarez in a spot like this on the road. The Cubs have done a good job this week rebounding from a loss, and they are the better team no matter how you slice it. Pomeranz doesn’t move the needle because he’s going to go 1 inning at best. Still, I’ll lean Cubs at home on Sunday.

Randy Chambers's Pick: Chicago Cubs

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