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Buffalo Bills vs New York Jets Prediction 9/14/2025 Today’s NFL Picks

Buffalo Bills quarterback Josh Allen fires off a pass during first half action against the Baltimore Ravens at Highmark Stadium in Orchard Park on Sept. 7, 2025.

Buffalo Bills quarterback Josh Allen fires off a pass during first half action against the Baltimore Ravens at Highmark Stadium in Orchard Park on Sept. 7, 2025.

MATCHUP Bills Buffalo Jets New York
Team Records 2-0 0-2
Where MetLife Stadium, East Rutherford, NJ
When Sunday, September 14, 2025
Time 01:00 PM EDT
TV CBS

The Buffalo Bills and the New York Jets meet in week 2 NFL action from MetLife Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Buffalo Bills vs. New York Jets prediction.

Buffalo Bills Recap

The Buffalo Bills come into this game looking to add on to their insane 41-40 season-opening win over the Baltimore Ravens last time out to sit at 1-0 this season. After this game, the Bills will head home for a matchup against the Miami Dolphins.

Bills Looking To Carry Over Momentum From Wild Win

Josh Allen threw for 394 yards and 2 touchdowns on 33 of 46 passing while also rushing for 30 yards and a pair of TDs as well. James Cook led the Bills on the ground with 44 rushing yards and a touchdown while Keon Coleman had a team-high 8 catches for 112 yards and a touchdown. Khalil Shakir had 6 grabs for 64 yards while Josh Palmer chipped in 61 receiving yards and the aforementioned Cook added 58 receiving yards as well. Dalton Kincaid also chipped in a receiving score for the Bills in the victory. On defense, Christian Benford had a team-high 7 total tackles including 5 solo tackles while Ed Oliver had 6 solo tackles and a sack. Matt Milano also chipped in a sack as well in the winning effort for the Bills.

New York Jets Recap

The New York Jets come into this game looking to rebound from a 34-32 loss at the hands of the Pittsburgh Steelers last time out to sit at 0-1 on the year. After this game, the Jets will head on the road for a game against the Tampa Bay Buccaneers.

Jets Looking For Bounce Back Showing

Justin Fields has thrown for 218 yards and a touchdown on 16 of 22 passing while also rushing for 48 yards and a pair of touchdowns. Breece Hall had 107 rushing yards on 19 carries and Braelon Allen added a rushing TD as well. Garrett Wilson also led the Jets with 7 catches for 95 yards and a touchdown as well in the losing effort. On defense, Quincy Williams led the charge with 6 total tackles including 4 solo tackles and a sack while Quinnen Williams also added a sack and Will McDonald IV had a pair of sacks as well in the defeat.

Buffalo Bills @ New York Jets Betting Trends: Week 2

Why the New York Jets will win

Why the Buffalo Bills will win

Total Points Facts

New York Jets Player Prop Facts

Buffalo Bills Player Prop Facts

Matchup/League Facts

Buffalo Bills vs. New York Jets Prediction

I’m on the Jets here with the points. I just think that while the Bills’ comeback against Baltimore was impressive, it left a lot to be desired for the Bills’ defense, who still allowed 40 points in that game. Granted, the Jets allowed 34 points to the Steelers, but they also scored 32 points against a solid Steeler defense, and I still think it’s a case of getting points with a home dog in a division matchup. I’ll take the points with the Jets at home in this one.

Chris Ruffolo's Pick: New York Jets +6.5

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