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Cincinnati Bengals vs Denver Broncos Prediction 9/29/2025 Today’s NFL Picks

Sep 21, 2025; Inglewood, California, USA;  Denver Broncos wide receiver Courtland Sutton (14) reaches for a long pass 4th down in the second half against the Los Angeles Chargers at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

Sep 21, 2025; Inglewood, California, USA; Denver Broncos wide receiver Courtland Sutton (14) reaches for a long pass 4th down in the second half against the Los Angeles Chargers at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

MATCHUP Bengals Cincinnati Broncos Denver
Team Records 2-1 1-2
Where Empower Field at Mile High, Denver, CO
When Monday, September 29, 2025
Time 08:15 PM EDT
TV ABC

The Cincinnati Bengals and Denver Broncos meet Monday in NFL action at Empower Field. Here’s a Cincinnati Bengals vs Denver Broncos Prediction. This article will include a Cincinnati Bengals vs Denver Broncos Pick.

With the Pittsburgh Steelers beating the Minnesota Vikings on Monday, there is pressure on the Bengals to keep pace in a tough AFC North. For the Broncos, the Chargers suffered a disappointing loss at the New York Giants, and this is their chance to move up a game. 

Cincinnati Bengals Betting Preview

The Cincinnati Bengals beat the Jaguars, lost to the Vikings, and they play the Lions next. The Cincinnati Bengals have won 7 of their last 8 games. Jake Browning is completing 67.8 percent of his passes for 381 yards, 3 touchdowns, and 5 interceptions. Ja’Marr Chase and Tee Higgins have combined for 345 receiving yards and 2 touchdowns, while Noah Fant has 12 receptions.

The Cincinnati Bengals ground game is averaging 49 yards per contest, and Chase Brown leads the way with 93 yards and 1 touchdown. Defensively, Cincinnati is allowing 30.3 points and 359.7 yards per game. Jordan Battle leads the Cincinnati Bengals with 23 tackles, Trey Hendrickson has 2 sacks and DJ Turner II has 1 interception.

Denver Broncos Betting Preview

The Denver Broncos lost to the Colts and Chargers, and they play the Eagles next. The Denver Broncos have won 6 of their last 10 games. Bo Nix is completing 64.2 percent of his passes for 535 yards, 5 touchdowns, and 3 interceptions. Courtland Sutton and Troy Franklin have combined for 326 receiving yards and 3 touchdowns, while Marvin Mims Jr. has 6 receptions.

The Denver Broncos ground game is averaging 129 yards per contest, and J.K. Dobbins leads the way with 222 yards and 3 touchdowns. Defensively, Denver is allowing 1.3 points and 327.3 yards per game. Talanoa Hufanga leads the Denver Broncos with 27 tackles, Nik Bonitto has 3 sacks and Brandon Jones has 1 interception.

Cincinnati Bengals @ Denver Broncos Betting Trends: Week 4

Why the Denver Broncos will win

Why the Cincinnati Bengals will win

Total Points Facts

Denver Broncos Player Prop Facts

Cincinnati Bengals Player Prop Facts

Matchup/League Facts

Cincinnati Bengals vs Denver Broncos Prediction

I’m not excited to lay a touchdown with a Broncos team that’s been shaky on both sides of the ball through 3 games, but I have no choice. The Bengals are still a mess defensively like they were last season, they can’t run the ball, and Browning has looked overwhelmed up to this point. We know what the Broncos are capable of defensively, and they should be able to frustrate this Bengals’ offense similar to what the Vikings did last week. The Broncos have covered 9 of their last 12 games as a favorite. I just don’t like the Bengals on either side of the ball. Give me the Broncos in an ugly double-digit victory.

Randy Chambers's Pick: Denver Broncos -7

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