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Los Angeles Chargers vs Las Vegas Raiders Prediction 9/15/2025 Today’s NFL Picks

Sep 7, 2025; Foxborough, Massachusetts, USA; Las Vegas Raiders running back Ashton Jeanty (2) rushes the ball against the New England Patriots during the second half at Gillette Stadium. Mandatory Credit: Bob DeChiara-Imagn Images

Sep 7, 2025; Foxborough, Massachusetts, USA; Las Vegas Raiders running back Ashton Jeanty (2) rushes the ball against the New England Patriots during the second half at Gillette Stadium. Mandatory Credit: Bob DeChiara-Imagn Images

MATCHUP Chargers Los Angeles Raiders Las Vegas
Team Records 1-0 1-0
Where Allegiant Stadium, Las Vegas, NV
When Monday, September 15, 2025
Time 10:00 PM EDT
TV ESPN

The Los Angeles Chargers and Las Vegas Raiders meet Monday in NFL action at Allegiant Stadium. Here’s a Los Angeles Chargers vs Las Vegas Raiders Prediction. This article will include a Los Angeles Chargers vs Las Vegas Raiders Pick.

Los Angeles Chargers Betting Preview

The Los Angeles Chargers beat the Chiefs, and they play the Broncos and Giants next. The Los Angeles Chargers have won 4 straight regular season games. Justin Herbert is completing 73.5 percent of his passes for 318 yards, 3 touchdowns, and 0 interceptions. Quentin Johnston and Ladd McConkey have combined for 153 receiving yards and 2 touchdowns, while Keenan Allen has 7 receptions.

The Los Angeles Chargers ground game is averaging 90 yards per contest, and Omarion Hampton leads the way with 48 yards on 15 carries. Defensively, Los Angeles is allowing 21 points and 347 yards per game. Alohi Gilman leads the Los Angeles Chargers with 9 tackles, Daiyan Henley has 1 sack and Teair Tart has 2 pass deflections.

Las Vegas Raiders Betting Preview

The Las Vegas Raiders beat the Patriots, and they play the Commanders and Bears next. The Las Vegas Raiders have won 3 of their last 4 games. Geno Smith is completing 70.6 percent of his passes for 362 yards, 1 touchdown, and 1 interception. Brock Bowers and Jakobi Meyers have combined for 200 receiving yards on 13 catches, while Tre Tucker has 2 receptions.

The Las Vegas Raiders ground game is averaging 56 yards per contest, and Ashton Jeanty leads the way with 38 yards and 1 touchdown. Defensively, Las Vegas is allowing 13 points and 336 yards per game. Devin White leads the Las Vegas Raiders with 11 tackles, Jonah Laulu has 1 sack and Isaiah Pola-Mao has 1 interception.

Los Angeles Chargers @ Las Vegas Raiders Betting Trends: Week 2

Why the Las Vegas Raiders will win

Why the Los Angeles Chargers will win

Total Points Facts

Las Vegas Raiders Player Prop Facts

Los Angeles Chargers Player Prop Facts

Matchup/League Facts

Los Angeles Chargers vs Las Vegas Raiders Prediction

You’re going to have chances to make money on the Raiders this season, as they’re going to be underdogs a lot, but there’s talent here. Geno pushes the ball down field, he has weapons, and the defense isn’t terrible. The Raiders can be better than many expect. However, the Chargers are simply the better team across the board, and they’ve had extra time to prepare for this game.

The team to win the last 10 games between the Chargers and Raiders is also 9-0-1 ATS. The Chargers are 11-3 ATS in their last 14 games as a favorite. This feels like a spot where the Raiders could have issues matching the Chargers score for score. I’ll take the Chargers by a touchdown.

Randy Chambers's Pick: Los Angeles Chargers -3

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