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Los Angeles Rams vs Tennessee Titans Prediction 9/14/2025 Today’s NFL Picks

Sep 7, 2025; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) attempts a pass during the first quarter at SoFi Stadium. Mandatory Credit: Kirby Lee-Imagn Images

Sep 7, 2025; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) attempts a pass during the first quarter at SoFi Stadium. Mandatory Credit: Kirby Lee-Imagn Images

MATCHUP Rams Los Angeles Titans Tennessee
Team Records 2-0 0-2
Where Nissan Stadium, Nashville, TN
When Sunday, September 14, 2025
Time 01:00 PM EDT
TV CBS

The Los Angeles Rams and the Tennessee Titans meet in week 2 NFL action from Nissan Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Rams vs. Tennessee Titans prediction.

Los Angeles Rams Recap

The Los Angeles Rams come into this game looking to add on to their season-opening 14-9 win over the Houston Texans to start the year 1-0. After this game, the Rams will head on the road for a game against the Philadelphia Eagles.

Rams Looking For Strong Start To Season

Matthew Stafford threw for 245 yards and a touchdown on 21 of 29 passing while Kyren Williams rushed for 66 yards and a touchdown. Puka Nacua led the Rams’ receiving group with 10 catches for 130 yards while Davante Adams had 4 catches for 51 yards and Davis Allen recorded the Rams’ lone receiving TD in the win. On defense, Kam Curl and Nate Landman each had a team-high 10 total tackles, while Byron Young, Tyler Davis and Jaylen McCollough each had a sack and Cobie Durant chipped in an interception for hte Rams defensively in the win.

Tennessee Titans Recap

The Tennessee Titans come into this game looking to rebound from their 20-12 loss at the hands of the Denver Broncos last time out to start the year at 0-1. After this game, the Titans will head home for a game against the Indianapolis Colts.

Titans Looking To Shake Off Opening Loss

Cam Ward threw for 112 yards on 12 of 28 pastting while Tony Pollard led the Titans on the ground with 60 rushing yards on 18 carries. Pollard led the Titans with 29 receiving yards while Calvin Ridley had a team-high 4 receptions for 27 yards and Chig Okonkwo added 3 receptions for 19 yards as well. On defense, Jarvis Brownlee Jr. and Cody Barton each had a team-high 9 total tackles with Brownlee Jr. adding 6 solo tackles while Jeffery Simmons had a sack. Xavier Woods and Roger McCreary each had an interception as well for Tennessee in the defeat. 

Los Angeles Rams @ Tennessee Titans Betting Trends: Week 2

Why the Tennessee Titans will win

Why the Los Angeles Rams will win

Total Points Facts

Tennessee Titans Player Prop Facts

Los Angeles Rams Player Prop Facts

Matchup/League Facts

Los Angeles Rams vs. Tennessee Titans Prediction

I’m on the under here. I wasn’t overly enthused with either side offensively in their openers, as the Rams just leaned heavily on their defense to get the job done, and the Titans still look like there’s going to be some definite growing pains to go through with Cam Ward under center. This to me feels like a first to 20 wins kind of game, so give me the under in this one.

Chris Ruffolo's Pick: Under 41.5

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